Oxovanadium(V) complexes with hydrazone ligands: Synthesis, characterization and biological activity

Jai Devi; Nisha Batra

首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Oxovanadium(V) complexes with hydrazone ligands: Synthesis, characterization and biological activity

【24h】

Oxovanadium(V) complexes with hydrazone ligands: Synthesis, characterization and biological activity

机译：ov配体的氧钒（V）配合物：合成，表征和生物活性。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

[VOSO4].5H20 with Pyrazine-2-carboxylic acid(phenyl-thiophene-2-yl-methylene)- hydrazide (HL1) and Pyrazine- 2-carboxylicacid (phenyl-pyridin-2-yl-methylene)-hydrazide (HL2), respectively, in methanol affords oxovanadium(V) complexes, [VO(SO4)L1] (I) and[VO(SO4)L2] (II). Both complexes have been characterized by elemental analysis and spectroscopic techniques (I.R, U.V, mass). The mononegative hydrazone ligands coordinate to the metal atoms through azomethine nitrogen, carbonyl oxygen and sulphur of thiophene ring (HL1)/ nitrogen of pyridine ring(HL2) and found to have square pyramidal geometry around each vanadium ion. Ligands and complexes were screened for in vitro antibacterial activity and antifungal activity at different concentrations against bacteria viz. Gram positive Bacillus subtilis, Micrococcus Luteus and Gram negative Pseudomonas aeruginosa, Pseudomonas mendocina and fungi Verticillum, Cladosporium, Tinospora. A distinct enrichment in biocidal activity of the ligands under similar experimental conditions was observed as a consequence of coordination with vanadium atom.

机译：[VOSO4] .5H20与吡嗪-2-羧酸（苯基-噻吩-2-基-亚甲基）-酰肼（HL1）和吡嗪-2-羧酸（苯基-吡啶-2--2-基-亚甲基）-酰肼（HL2）分别在甲醇中提供氧钒（V）络合物[VO（SO4）L1]（I）和[VO（SO4）L2]（II）。两种配合物均已通过元素分析和光谱技术（I.R，U.V，质量）进行了表征。单负mono配体通过偶氮甲碱氮，噻吩环（HL1）的羰基氧和硫/吡啶环（HL2）的氮与金属原子配位，并在每个钒离子周围具有方形金字塔形状。筛选配体和复合物在不同浓度下对细菌的体外抗菌活性和抗真菌活性。革兰氏阳性枯草芽孢杆菌，黄球微球菌和革兰氏阴性铜绿假单胞菌，mendocina假单胞菌和黄萎病菌，枝孢菌，丁香孢。由于与钒原子配位，在相似的实验条件下观察到配体具有明显的杀生物活性富集。

著录项

来源
《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2013年第1期|共7页
作者
Jai Devi; Nisha Batra;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Neutral dioxovanadium(V) complexes of biomimetic hydrazones ONO donor ligands of bioinorganic and medicinal relevance: Synthesis via air oxidation of bis(acetylaceto-nato)oxovanadium(IV), characterization, biological activity and 3D molecular modelin [J] . R.C. Maurya, S. Rajput Journal of Molecular Structure . 2007,第1a3期

机译：仿生的中性二氧钒钒（V）络合物与生物无机和药物相关性的ONO供体配体：双（乙酰乙酰-萘）氧钒（IV）的空气氧化合成，表征，生物活性和3D分子模型
2. Synthesis, crystal structures, and biological activity of oxovanadium(V) complexes with similar tridentate hydrazone ligands [J] . GUI-HUA SHENG, XIAO HAN, ZHONGLU YOU Journal of Coordination Chemistry . 2014,第9a10期

机译：具有类似三齿配体的氧钒（V）配合物的合成，晶体结构和生物活性
3. Synthesis and characterization of new transition and actinide metal complexes of a hydrazone ligand. Mixed-ligand complexes, pyrolysis products, and biological activity [J] . Mashaly MM, Ramadan AT, El-Shetary BA, Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry . 2004,第8期

机译：ligand配体的新过渡金属和act系金属配合物的合成与表征。混合配体配合物，热解产物和生物活性
4. Synthesis, Characterization and Biological Activity Evaluation of Novel Pd(II) and Pt(II) Complexes with Heterocyclic Hydrazone Ligands [C] . N. R. Filipovic, T. R. Todorovic, D. M. Sladic, Yugoslav Materials Restarch Society Conference . 2007

机译：用杂环腙配体的新型Pd（II）和Pt（II）配合物的合成，表征和生物活性评价
5. Synthesis, characterization, and reactivity of titanium-ligand multiply bonded complexes supported by sterically encumbering β-diketiminate and PNP pincer -type ligands [D] . Bailey, Brad Cameron 2007

机译：位阻性β-二酮和PNP钳型配体支持的钛-配体多重键合配合物的合成，表征和反应性
6. Synthesis Characterization and Biological Activities of Cu(II) Co(II) Mn(II) Fe(II) and UO2(VI) Complexes with a New Schiff Base Hydrazone: O-Hydroxyacetophenone-7-chloro-4-quinoline Hydrazone [O] . Nora H. Al-Shaalan 2011

机译：具有新型席夫碱Hy的Cu（II）Co（II）Mn（II）Fe（II）和UO2（VI）配合物的合成表征和生物活性：O-羟基乙酰苯酮-7-chloro-4-喹Hy Hy
7. Synthesis, Characterization and Biological Activities of Cu(II), Co(II), Mn(II), Fe(II), and UO2(VI) Complexes with a New Schiff Base Hydrazone: O-Hydroxyacetophenone-7-chloro-4-quinoline Hydrazone [O] . Nora H. Al-Shaalan 2011

机译：具有新型席夫碱Hy的Cu（II），Co（II），Mn（II），Fe（II）和UO2（VI）配合物的合成，表征和生物活性：O-羟基乙酰苯-7-chloro-4-喹Hy Hy

Oxovanadium(V) complexes with hydrazone ligands: Synthesis, characterization and biological activity

摘要

著录项

相似文献

相关主题

期刊订阅