Synthesis and characterization of some novel isoxazoles via chalcone intermediates

Kapubalu Suneel Kumar; Kovvuri Tatendra Reddy; Appikonda Vamsikanth; Gudaparthi Omprakash; P. K. Dubey

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Synthesis and characterization of some novel isoxazoles via chalcone intermediates

机译：查尔酮中间体合成和表征一些新型异恶唑

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The synthesis and characterization of some novel isoxazoles derivatives have been presented. Acylation of resorcinol followed by nuclear prenylation with isoprene gives Chroman. Chroman on treatment with p-substituted benzaldehydes affords substituted chalcones. Isoxazoles have been prepared from chalcones by treating with hydroxylamine hydrochloride. The structure of isoxazoles has been characterized by spectral analysis.

机译：已经提出了一些新型异恶唑衍生物的合成和表征。将间苯二酚酰化，然后用异戊二烯进行核异戊烯化，得到色氨酸。用对位取代的苯甲醛处理的色氨酸得到取代的查耳酮。通过用盐酸羟胺处理，从查耳酮制备了异恶唑。异恶唑的结构已通过光谱分析表征。

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《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2011年第5期|共10页
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Kapubalu Suneel Kumar; Kovvuri Tatendra Reddy; Appikonda Vamsikanth; Gudaparthi Omprakash; P. K. Dubey;
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中图分类化学;
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2. Facile synthesis of alkoxyphthalimide derivatized benzimidazole assembled pyrazoles, pyrimidines and isoxazoles, via common intermediate chalcone [J] . Archita Bapna, Swati Ojha, G L Talesara Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2008,第7期

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Synthesis and characterization of some novel isoxazoles via chalcone intermediates

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