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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Comparative Evaluation of the Antiradical and Antimicrobial Activities of Organic Extracts of Algerian Pulicaria arabica (L.) Cass. with Reference Products
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Comparative Evaluation of the Antiradical and Antimicrobial Activities of Organic Extracts of Algerian Pulicaria arabica (L.) Cass. with Reference Products

机译：阿尔及利亚Pulsaria arabica（L.）Cass有机提取物的抗自由基和抗菌活性的比较评价。与参考产品

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This study is to assess the antimicrobial and antiradical activities of organic extracts from the species Pulicaria arabica (L.) Cass. We used four clinical strains and four reference strains, to assess the antimicrobial activity of organic extracts of P. Arabica (L.) Cass. Evaluation of the antiradical activity is done by spectroscopic assay using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. Measurement of the antiradical activity of three plant extracts was carried out using the DPPH test. The anti-radical tests of ours extracts were assessed using the free radicals DPPH catching method. The results showed clearly, that the methanol extract (EMeOH) had the best anti-radical ability followed by chloroform extract (EDCM) and lastly the hexane extract (In-Hex). The antimicrobial tests were evaluated against reference pathogenic strains and others isolated from pathological materials, using agar diffusion method. The results indicated that the apolar extracts (hexane and chloroform) had inhibitory activity against a number of microorganisms higher than that of the polar methanolic extract. Antimicrobial and antiradical activities of organic extracts from the species Pulicaria arabica (L.) Cass has shown that these extracts have considerable inhibitory activity against certain germs and good potential of DPPH free radical scavenging, but these activities are generally lower than those obtained with the reference products (antibiotics, antifungal and ascorbic acid).
机译：这项研究旨在评估来自阿拉伯木栗（Pulicaaria arabica（L.）Cass）物种的有机提取物的抗微生物和抗自由基活性。我们使用了四个临床菌株和四个参考菌株，以评估阿拉伯拟南芥（L.）Cass有机提取物的抗菌活性。使用DPPH（1,1-二苯基-2-吡咯并肼基）方法通过光谱测定法评估抗自由基活性。使用DPPH测试对三种植物提取物的抗自由基活性进行了测量。我们的提取物的抗自由基测试采用自由基DPPH捕获法进行评估。结果清楚地表明，甲醇萃取物（EMeOH）具有最佳的抗自由基能力，其次是氯仿萃取物（EDCM），最后是己烷萃取物（In-Hex）。使用琼脂扩散法对参考病原菌株和从病理材料分离出的其他菌株进行了抗微生物测试。结果表明，非极性提取物（己烷和氯仿）对多种微生物的抑制活性高于极性甲醇提取物。阿拉伯Pulicaria arabica（L.）Cass物种的有机提取物的抗菌和抗自由基活性表明，这些提取物对某些细菌具有相当大的抑制活性，并具有清除DPPH自由基的良好潜力，但这些活性通常低于参考文献中获得的活性。产品（抗生素，抗真菌药和抗坏血酸）。

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