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首页> 外文期刊>Dhaka University Journal of Pharmaceutical Sciences >Comparative Phytochemical, Antioxidant and Antimicrobial Properties of Ficus capensis, Aristolochia ringens, Albizia zygia and Lannea welwitschii
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Comparative Phytochemical, Antioxidant and Antimicrobial Properties of Ficus capensis, Aristolochia ringens, Albizia zygia and Lannea welwitschii

机译:榕树,马兜铃,合欢和兰芝的植物化学,抗氧化和抗菌性能比较

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The present study was aimed at a comparative study of the phytoconstituents, antioxidant and antimicrobial properties of four medicinal plants, Ficus capensis, Aristolochia ringens, Albizia zygia and Lannea welwitschii. The leaf of F. capensis and stem bark of A. ringens, A. zygia and L. welwitschii were extracted using methanol. Phytochemical analysis was done spectrophotometrically. Three in vitro antioxidant tests-hydrogen peroxide (H2O2), nitric oxide (NO) and 2, 2-diphenyl-1-picrylhydroxyl (DPPH) scavenging models were employed. Antimicrobial test was done by agar diffusion method against E. coli, Staphylococcus aureus, Klebsiela pneumonia, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Candida albicans and Aspergittus spp. Phytochemical analysis revealed that the most abundant phytoconstituents were flavonoids (F. capensis and A. zygia), reducing sugar, terpenoids, alkaloids and tannins. In the antioxidant models, A. zygia was found to produce the least IC50 in two of the models (NO and DPPH). Results of the antimicrobial tests showed that A. zygia showed a broader spectrum of activity than other plants. This study has shown that these plants possess antioxidant and antimicrobial activities which further justify their usage in traditional medicines. A. zygia featured prominently in these activities. Also flavonoids could be responsible for the bioactivities of these plants.Dhaka Univ. J. Pharm. Sci. 16(2): 147-157, 2017 (December)
机译:本研究旨在对四种药用植物(无花果榕,马兜铃,Al木和and)的药用成分,抗氧化剂和抗菌特性进行比较研究。用甲醇提取山茱F的叶子和林蛙,木和and木的茎皮。分光光度法进行植物化学分析。使用了三种体外抗氧化剂测试-过氧化氢(H2O2),一氧化氮(NO)和2,2-二苯基-1-吡啶羟基(DPPH)清除模型。通过琼脂扩散法对大肠杆菌,金黄色葡萄球菌,肺炎克雷伯菌,枯草芽孢杆菌,铜绿假单胞菌,鼠伤寒沙门氏菌,白色念珠菌和曲霉进行了抗菌测试。植物化学分析表明,最丰富的植物成分是黄酮类化合物(卡普桑(F. capensis)和曲霉(A. zygia)),还原糖,萜类,生物碱和单宁酸。在抗氧化剂模型中,发现A. zygia在两个模型(NO和DPPH)中产生的IC50最小。抗菌测试结果表明,A。zygia具有比其他植物更广泛的活性谱。这项研究表明,这些植物具有抗氧化和抗菌活性,这进一步证明了它们在传统药物中的应用。在这些活动中,A。zygia表现突出。黄酮类化合物也可能是这些植物的生物活性的原因。 J.药物科学16(2):147-157,2017(十二月)

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