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Pancreaticopleural Fistula: Revisited

机译:胰胸膜瘘

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Pancreaticopleural fistula is a rare complication of acute and chronic pancreatitis. This usually presents with chest symptoms due to pleural effusion, pleural pseudocyst, or mediastinal pseudocyst. Diagnosis requires a high index of clinical suspicion in patients who develop alcohol-induced pancreatitis and present with pleural effusion which is recurrent or persistent. Analysis of pleural fluid for raised amylase will confirm the diagnosis and investigations like CT. Endoscopic retrograde cholangiopancreaticography (ECRP) or magnetic resonance cholangiopancreaticography (MRCP) may establish the fistulous communication between the pancreas and pleural cavity. The optimal treatment strategy has traditionally been medical management with exocrine suppression with octreotide and ERCP stenting of the fistulous pancreatic duct. Operative therapy considered in the event patient fails to respond to conservative management. There is, however, a lack of clarity regarding the management, and the literature is reviewed here to assess the present view on its pathogenesis, investigations, and management.
机译:胰腺胸膜瘘是急,慢性胰腺炎的罕见并发症。通常由于胸腔积液,胸膜假性囊肿或纵隔假性囊肿而出现胸部症状。对于发展为酒精性胰腺炎并反复或持续存在胸腔积液的患者,诊断需要高度的临床怀疑。胸膜液中淀粉酶升高的分析将证实诊断和检查,如CT。内镜逆行胰胆管造影(ECRP)或磁共振胆胰管造影(MRCP)可在胰腺和胸膜腔之间建立瘘管通气。传统上,最佳治疗策略是采用奥曲肽抑制外分泌,并在瘘管内置入ERCP支架来进行药物治疗。如果患者对保守治疗没有反应,则考虑进行手术治疗。然而,关于治疗尚缺乏明确性,这里对文献进行回顾以评估其发病机理,研究和治疗的当前观点。

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