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Gastric Cancer Profile in Kashmiri Population With Special Dietary Habits

机译:有特殊饮食习惯的克什米尔居民中的胃癌概况

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The present study is a comprehensive retrospective analysis of 1341 gastric neoplasms out of10 733 individuals subjected to upper gastrointestinal endoscopy at the main teaching cumreferral hospital in the Kashmir Valley. Of these 78% were males and 22% females, majoritybeing in the age group of 41–60 years with 60% of the patients being smokers. On endoscopy,the commonest site of cancer was the body of stomach 40.7%, followed by the antrum 35.5%and the cardiac region 23.8%. Endoscopic features revealed nodular masses 39%, polypoidmasses 21%, malignant ulcers 11%, infiltrative masses 12%, rounded tumor masses 9%,linitus plastica 5% and early gastric carcinoma 3%. Histology revealed adenocarcinoma91%, (including mucoid carcinoma 9%, and schirrous carcinoma 7%), leiomyosarcoma 7%,and reticulum cell sarcoma 2%. No significant association betweenHelicobacter pyloriinfection and gastric cancer was observed in a short study out of these patients. The peculiargeography and some special dietary habits with a possible familial predisposition may havea bearing on the high risk of gastric cancer in the valley.
机译:本研究是对克什米尔河谷主要教学附属医院接受上消化道内镜检查的10 733名个体中的1341例胃肿瘤的综合回顾性分析。在这78%中,男性为2​​2%,女性为22%,年龄段在41-60岁之间,其中60%是吸烟者。在内窥镜检查中,最常见的癌症部位是胃体40.7%,其次是胃窦35.5%和心脏区域23.8%。内窥镜检查显示结节性肿块39%,息肉样肿块21%,恶性溃疡11%,浸润性肿块12%,圆形肿瘤肿块9%,可塑性5%,早期胃癌3%。组织学检查显示腺癌为91%(包括粘液样癌为9%,鳞状癌为7%),平滑肌肉瘤为7%,网状细胞肉瘤为2%。在一项简短的研究中,这些患者中没有发现幽门螺杆菌感染与胃癌之间的显着相关性。特殊的地理环境和一些特殊的饮食习惯以及可能的家族易感性可能与山谷中患胃癌的高风险有关。

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