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首页> 外文期刊>The Egyptian Journal of Hospital Medicine >Pregnancy Outcome after Difficult Embryo Transfer in IVF-ET Cycles
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Pregnancy Outcome after Difficult Embryo Transfer in IVF-ET Cycles

机译：IVF-ET周期中难于移植胚胎后的妊娠结局

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Background: Embryo transfer (ET) is one of the most crucial steps in IVF/ICSI treatment. Although it, apparently, seems simple, it is an integral part of IVF/ICSI and can affect the outcome of the whole treatment cycle. The majority of couples (approximately 80%) who undergo IVF reach the ET stage, yet few pregnancies occur. The pregnancy rate after ET is dependent on multiple factors including embryo quality, endometrial receptivity, and the technique of the ET. Aim of the Work: The aim of the current study is to investigate the clinical and ongoing clinical pregnancy rates in women who experience difficult embryo transfer (ET) after IVF/ICSI cycle. Patients and Methods: This prospective cohort study was conducted at Dar Al-Teb Infertility and IVF Center between January 2017 and January 2018. The study included 417 women planned to undergo ET. Results: The biochemical, clinical and ongoing clinical pregnancy rates were significantly lower in women who had difficult ET when compared to women who had easy ET [ORs 0.5, 95% CI (0.31 to 0.83); 0.48, 95% CI (0.29 to 0.79); 0.36, 95% CI (0.21 to 0.62); respectively]. Conclusion: Difficult ET is associated with significantly reduced biochemical, clinical and ongoing clinical pregnancy rates. Recommendations: ET should be smooth with easy passage of the transfer catheter. Since any uterine manipulation during ET adversely affects IVF results, therefore precaution should be taken to identify possibly difficult ET cases in advance.
机译：背景：胚胎移植（ET）是IVF / ICSI治疗中最关键的步骤之一。尽管它看起来很简单，但它是IVF / ICSI不可或缺的一部分，并可能影响整个治疗周期的结果。大多数接受试管婴儿的夫妇（约80％）已进入ET阶段，但很少发生怀孕。 ET后的妊娠率取决于多种因素，包括胚胎质量，子宫内膜的接受性和ET的技术。工作目的：本研究的目的是调查IVF / ICSI周期后经历困难胚胎移植（ET）的妇女的临床和正在进行的临床妊娠率。患者和方法：这项前瞻性队列研究于2017年1月至2018年1月期间在Dar Al-Teb不孕症和IVF中心进行。该研究包括417名计划进行ET的女性。结果：ET困难妇女的生化，临床和正在进行的临床妊娠率显着低于ET容易妇女[OR分别为0.5、95％CI（0.31至0.83）; 0.48，95％CI（0.29至0.79）; 0.36，95％CI（0.21至0.62）;分别]。结论：困难的ET与生化，临床和正在进行的临床妊娠率显着降低有关。建议：ET应当光滑，并易于通过转移导管。由于在ET期间进行任何子宫操作都会对IVF结果产生不利影响，因此应采取预防措施，以提前发现可能困难的ET病例。

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