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Microscopic Colitis is Associated with Several Concomitant Diseases

机译：微观结肠炎与几种伴随疾病有关

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Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been described, although not compared with controls or adjusted for confounding factors. The aim of this study was to examine the prevalence of common diseases in patients with MC and controls from the general population. Hypertension, rheumatoid arthritis, asthma or bronchitis, ischemia, and diabetes mellitus were more prevalent in patients than in controls. The prevalence of gastric ulcer and cancer did not differ between the groups. Besides corticosteroids, many patients were also being treated with proton pump inhibitors, antidepressant drugs, angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists, statins, thyroid hormones, and beta-blockers. More patients than controls were former or current smokers (72.5% versus 57.7%). Thus, MC patients have an increased prevalence of several diseases, not only of autoimmune origin.
机译：显微镜结肠炎（MC）是一种具有肠道粘膜炎症的疾病，可引起腹泻，主要影响中年妇女。病因不明，但已描述了这些患者自身免疫性疾病的患病率增加，尽管未与对照进行比较或未针对混杂因素进行调整。这项研究的目的是检查普通人群中MC患者和对照患者的常见疾病患病率。与对照组相比，患者中高血压，类风湿性关节炎，哮喘或支气管炎，局部缺血和糖尿病的患病率更高。两组之间胃溃疡和癌症的患病率没有差异。除皮质类固醇激素外，许多患者还接受了质子泵抑制剂，抗抑郁药，血管紧张素转换酶抑制剂或血管紧张素II受体拮抗剂，他汀类药物，甲状腺激素和β受体阻滞剂的治疗。曾经吸烟或现在吸烟的患者比对照组多（分别为72.5％和57.7％）。因此，MC患者不仅自身免疫源性疾病的患病率增加。

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