• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Drug Target Insights >Valacyclovir Neurotoxicity and Nephrotoxicity in an Elderly Patient Complicated by Hyponatremia
【24h】

Valacyclovir Neurotoxicity and Nephrotoxicity in an Elderly Patient Complicated by Hyponatremia

机译：缬沙洛韦对低钠血症并发老年患者的神经毒性和肾毒性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A 66-year-old women with no history of renal disease was admitted due to a coma and acute kidney injury with a serum creatinine level of 7.44?mg/dL which were ascribed to valacyclovir neurotoxicity and nephrotoxicity, respectively. She had received valacyclovir at a standard dosage for the treatment of herpes zoster and was finally discharged, having fully returned to her normal baseline mental status with a recovered serum creatinine level of 0.68?mg/dL. We feel that awareness of this pathology remains a challenge for physicians and therefore strongly recommend the further accumulation of experiences similar to our own. Our experience underscores the pitfalls of administering valacyclovir to elderly patients who barely appear to have a favorable renal function. Several concerns regarding the therapeutic management, including blood purification strategies, that emerged in this case are also discussed.
机译：一名66岁的无肾脏疾病史的妇女因昏迷和急性肾损伤而入院，血清肌酐水平为7.44？mg / dL，分别归因于伐昔洛韦神经毒性和肾毒性。她已接受标准剂量的伐昔洛韦治疗带状疱疹，最终出院，完全恢复到正常的基线精神状态，血清肌酐水平恢复为0.68？mg / dL。我们认为，对这种病理学的认识仍然是医师的挑战，因此强烈建议进一步积累与我们类似的经验。我们的经验强调了向几乎没有良好肾功能的老年患者服用伐昔洛韦的陷阱。还讨论了在这种情况下出现的有关治疗管理的若干问题，包括血液净化策略。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号