...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>JMIR public health and surveillance. >Monitoring Prevention Impact of Mother-to-Child Transmission of HIV in Concentrated Epidemics With Program and Survey Data
【24h】

Monitoring Prevention Impact of Mother-to-Child Transmission of HIV in Concentrated Epidemics With Program and Survey Data

机译：通过计划和调查数据监测母婴传播艾滋病毒在集中流行中的预防影响

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The prevention of mother-to-child transmission (PMTCT) of HIV program was introduced in Vietnam in 2005. Despite the scaling up of PMTCT programs, the rate of mother-to-child HIV transmission in Vietnam was estimated as high as 20% in 2013. Objective: The objective of this study was to assess the outcomes of PMTCT and identified factors associated with mother-to-child transmission and infant survival using survey and program data in a high HIV burden province in Vietnam. Methods: This community-based retrospective cohort study observed pregnant women diagnosed with HIV infection in Thai Nguyen province from October 2008 to December 2012. Data were collected through interviews using a structured questionnaire and through reviews of log books and medical charts in antenatal care and HIV clinics. Logistic regression and survival analysis were used to analyze data using Stata (StataCorp). Results: A total of 172 pregnant women living with HIV were identified between 2008 and 2012. Most of these women had acquired the HIV infection from their husband (77/119, 64.7%). Significant improvement in the PMTCT program was documented, including reduction in late diagnosis of HIV for pregnant women from 62.5% in 2008 to 30% in 2012. Access to antiretrovirals (ARVs) improved, increasing from a rate of 18.2% (2008) to 70.0% (2011) for mothers and from 36.4% (2008) to 93.3% (2012) for infants. For infants, early diagnosis within 2 months of birth reached 66.7% in 2012 compared with 16.7% in 2009. Transmission rate reduced from 27.3% in 2008 to 6.7% in 2012. Late diagnosis was associated with increased risk for HIV transmission (odds ratio [OR] 14.7, 95% CI 1.8-121.4, P =.01), whereas ARV therapy for mother and infant in combination with infant formula feeding were associated with reduced risk for HIV transmission (OR 0.01, 95% CI 0.001-0.1; P .001). Overall survival rate for HIV-exposed infants at 12 months was 97.7%. Conclusions: A combination of program and survey data measured the impact of prevention of HIV transmission from mother-to-child interventions. Significant improvement in access to the interventions was documented in Thai Nguyen province. However, factors that increased the risk of HIV transmission, such as late diagnosis, remain to be addressed.
机译：背景：越南于2005年引入了预防艾滋病毒母婴传播计划。尽管扩大了母婴传播计划，但越南的母婴艾滋病毒传播率估计高达20 2013年的百分比。目的：本研究的目的是使用越南艾滋病毒高负担省份的调查和计划数据评估PMTCT的结局​​，并确定与母婴传播和婴儿存活率相关的因素。方法：这项基于社区的回顾性队列研究观察了泰国阮省从2008年10月至2012年12月被诊断患有HIV感染的孕妇。使用结构化问卷通过访谈收集数据，并通过回顾产前保健和HIV中的日志和医学图表进行收集诊所。 Logistic回归和生存分析用于使用Stata（StataCorp）分析数据。结果：在2008年至2012年之间，共鉴定出172名艾滋病毒孕妇。这些孕妇中大多数是从丈夫那里感染艾滋病毒的（77 / 119，64.7％）。记录了PMTCT计划的显着改善，包括孕妇艾滋病毒的晚期诊断率从2008年的62.5％降低到2012年的30％。获得抗逆转录病毒药物（ARV）的比例从18.2％（2008）上升到70.0母亲的百分比（2011），婴儿的36.4％（2008）到93.3％（2012）。婴儿的出生后两个月内，早期诊断在2012年达到66.7％，而2009年为16.7％。传播率从2008年的27.3％降至2012年的6.7％。晚期诊断与HIV传播风险增加相关（几率[ OR] 14.7，95％CI 1.8-121.4，P = .01），而母亲和婴儿的抗逆转录病毒疗法联合婴儿配方奶粉喂养可降低HIV传播风险（OR 0.01，95％CI 0.001-0.1; P <.001）。感染艾滋病毒的婴儿在12个月时的总生存率为97.7％。结论：计划和调查数据相结合，测量了预防母婴干预措施传播HIV的影响。泰国阮省记录了干预措施获得显着改善。但是，增加艾滋病毒传播风险的因素，例如晚期诊断，仍有待解决。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号