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Accuracy of low dose CT in the diagnosis of appendicitis in childhood and comparison with USG and standard dose CT ?¢????

机译:低剂量CT诊断儿童阑尾炎的准确性以及与USG和标准剂量CT的比较

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Abstract Objectives: Computed tomography should be performed after careful consideration due to radiation hazard, which is why interest in low dose CT has increased recently in acute appendicitis. Previous studies have been performed in adult and adolescents populations, but no studies have reported on the efficacy of using low-dose CT in children younger than 10 years. Methods: Patients ( n = 475) younger than 10 years who were examined for acute appendicitis were recruited. Subjects were divided into three groups according to the examinations performed: low-dose CT, ultrasonography, and standard-dose CT. Subjects were categorized according to age and body mass index (BMI). Results: Low-dose CT was a contributive tool in diagnosing appendicitis, and it was an adequate method, when compared with ultrasonography and standard-dose CT in terms of sensitivity (95.5% vs . 95.0% and 94.5%, p = 0.794), specificity (94.9% vs. 80.0% and 98.8%, p = 0.024), positive-predictive value (96.4% vs . 92.7% and 97.2%, p = 0.019), and negative-predictive value (93.7% vs . 85.7% and 91.3%, p = 0.890). Low-dose CT accurately diagnosed patients with a perforated appendix. Acute appendicitis was effectively diagnosed using low-dose CT in both early and middle childhood. BMI did not influence the accuracy of detecting acute appendicitis on low-dose CT. Conclusion: Low-dose CT is effective and accurate for diagnosing acute appendicitis in childhood, as well as in adolescents and young adults. Additionally, low-dose CT was relatively accurate, irrespective of age or BMI, for detecting acute appendicitis. Therefore, low-dose CT is recommended for assessing children with suspected acute appendicitis.
机译:摘要目的:由于放射线危害,应在仔细考虑后进行计算机体层摄影,这就是为什么最近对急性阑尾炎对低剂量CT的关注增加的原因。先前的研究已经在成人和青少年人群中进行,但尚无任何研究报道低剂量CT对10岁以下儿童的疗效。方法:招募了年龄小于10岁的急性阑尾炎患者(n = 475)。根据所进行的检查,将受试者分为三组:低剂量CT,超声检查和标准剂量CT。根据年龄和体重指数(BMI)对受试者进行分类。结果:低剂量CT是诊断阑尾炎的重要工具,与超声检查和标准剂量CT相比,灵敏度高(95.5%vs. 95.0%和94.5%,p = 0.794),它是一种适当的方法,特异性(94.9%对80.0%和98.8%,p = 0.024),阳性预测值(96.4%对92.7%和97.2%,p = 0.019)和阴性预测值(93.7%对85.7%和91.3%,p = 0.890)。小剂量CT可准确诊断出阑尾穿孔的患者。在儿童早期和中期,使用小剂量CT可有效诊断急性阑尾炎。 BMI不影响小剂量CT上检测急性阑尾炎的准确性。结论:小剂量CT对儿童以及青少年和青年人的急性阑尾炎诊断有效且准确。此外,无论年龄或BMI,低剂量CT都可相对准确地检测急性阑尾炎。因此,建议使用低剂量CT评估疑似急性阑尾炎的儿童。

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