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首页> 外文期刊>Journal of athletic training >Practice-Based Research Networks, Part I: Clinical Laboratories to Generate and Translate Research Findings Into Effective Patient Care
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Practice-Based Research Networks, Part I: Clinical Laboratories to Generate and Translate Research Findings Into Effective Patient Care

机译：基于实践的研究网络，第一部分：临床实验室，以生成研究结果并将其转化为有效的患者护理

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Context: To improve patient care, athletic training clinicians and researchers should work together to translate research findings into clinical practice. Problems with patient care observed in clinical practice should be translated into research frameworks, where they can be studied. Practice-based research networks (PBRNs) provide a compelling model for linking clinicians and researchers so they can conduct translational research to improve patient care. Objective: To describe (1) the translational research model, (2) practice-based research as a mechanism for translating research findings into clinical practice, (3) the PBRN model and infrastructure, (4) the research potential using the PBRN model, and (5) protection of human participants in PBRN research. Description: Translational research is the process of transforming research findings into health behavior that ultimately serves the public and attempts to bridge the gap between research and clinical practice. Practice-based research represents the final step in the translational research continuum and describes research conducted by providers in clinical practices. The PBRNs are characterized by an organizational framework that transcends a single site or study and serves as the clinical research “laboratory” for conducting comparative-effectiveness studies using patient-oriented measures. The PBRN approach to research has many benefits, including enhanced generalizability of results, pooling of resources, rapid patient recruitment, and collaborative opportunities. However, multisite research also brings challenges related to the protection of human participants and institutional review board oversight. Clinical and Research Advantages: Athletic training studies frequently include relatively few participants and, consequently, are able to detect only large effects. The incidence of injury at a single site is sufficiently low that gathering enough data to adequately power a treatment study may take many years. Collaborative efforts across diverse clinical practice environments can yield larger patient samples to overcome the limitations inherent in single-site research efforts.
机译：背景：为了改善患者护理，运动训练的临床医生和研究人员应共同努力，将研究结果转化为临床实践。临床实践中观察到的患者护理问题应转化为研究框架，以便在其中进行研究。基于实践的研究网络（PBRN）为连接临床医生和研究人员提供了一种引人注目的模型，因此他们可以进行转化研究以改善患者护理。目的：描述（1）转化研究模型，（2）基于实践的研究作为将研究结果转化为临床实践的机制，（3）PBRN模型和基础设施，（4）使用PBRN模型的研究潜力， （5）保护PBRN研究中的人类参与者。描述：转化研究是将研究结果转化为健康行为的过程，最终为公众服​​务，并试图弥合研究与临床实践之间的鸿沟。基于实践的研究代表了转化研究连续性的最后一步，并描述了提供者在临床实践中进行的研究。 PBRN的特点是组织结构跨越单个站点或研究，并成为临床研究的“实验室”，用于使用以患者为中心的措施进行相对有效性研究。 PBRN研究方法具有许多好处，包括增强结果的通用性，资源共享，快速招募患者和协作机会。但是，多站点研究也带来了与保护人类参与者和机构审查委员会监督相关的挑战。临床和研究的优势：运动训练研究通常只包括相对较少的参与者，因此只能发现较大的影响。单个地点的伤害发生率足够低，以至于收集足够的数据来充分支持治疗研究可能需要很多年。跨各种临床实践环境的协作可以产生更大的患者样本，以克服单站点研究工作固有的局限性。

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