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首页> 外文期刊>Journal of Behavioral and Brain Science >Brain Signaling in Psychiatric Disorders: What Can They Tell Us in the Absence of Behavioral Differences?
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Brain Signaling in Psychiatric Disorders: What Can They Tell Us in the Absence of Behavioral Differences?

机译：精神疾病中的脑信号：在没有行为差异的情况下他们能告诉我们什么？

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This is a commentary on the often-observed phenomenon of observing task-based brain signaling differences between clinical populations and healthy control participants in the absence of any behavioral decrements in the clinical group. We offer several explanations for why brain-based differences amid normative performance may be of interest to researchers and clinicians. First, neural processing in the clinical group may not be as efficient as that in the control group. Second, differences in activation could reveal important differences in the cognition behind the (normative) behavior. Third, differences in activation may be prognostic biomarkers of injury or decline. In addition, we contend that similar behavior between groups is important in properly interpreting brain data. Finally, we offer caveats and future directions to further clarify brain mechanisms underlying behavior in clinical populations.
机译：这是对在临床人群中没有任何行为减量的情况下观察临床人群与健康对照参与者之间基于任务的脑信号差异的常见现象的评论。我们提供了几种解释，说明为什么规范性表现中基于脑的差异可能引起研究人员和临床医生的兴趣。首先，临床组的神经处理可能不如对照组有效。其次，激活的差异可能揭示（规范）行为背后的认知上的重要差异。第三，激活差异可能是损伤或衰退的预后生物标志物。此外，我们认为，群体之间的相似行为对于正确解释大脑数据很重要。最后，我们提供了警告和未来的方向，以进一步阐明临床人群行为背后的大脑机制。

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