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A Novel Micro Flow-Focusing Device for the Control of Droplet Contents

机译:一种新型的微滴控制装置

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Micro flow-focusing devices (mFFDs) have been used extensively to produce emulsions and for the on-line encapsulation of biologic objects, such as bacteria and cells. More recently, new designs of this type of instrument have been imagined, for example to produce multi-layered capsules. In this work, we present a novel design of mFFD that comprises “moustaches”, i.e. escape microchannels, just upstream of the orifice. In the context of encapsulation, such a design authorizes the control of the number of biologic objects imprisoned in a single capsule, and avoids the emission of empty capsules. We have denoted this new type of FFD by the abbreviation EFFD, for “Escape FFD”. We first present the concept of the system, then we derive the pressure conditions for the proper functioning of the device, and finally we present an experimental realization.
机译:微流聚焦装置(mFFD)已被广泛用于生产乳剂和用于生物物体(如细菌和细胞)的在线封装。最近,已经想到了这种类型的仪器的新设计,例如以生产多层胶囊。在这项工作中,我们提出了一种新颖的mFFD设计,该设计包括孔口上游的“小胡子”,即逸出微通道。在封装的情况下,这样的设计授权控制囚禁在单个胶囊中的生物物体的数量,并避免空胶囊的散发。我们用缩写EFFD来表示这种新型FFD,即“逃逸FFD”。我们首先介绍系统的概念,然后得出用于设备正常运行的压力条件,最后介绍实验性实现。

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