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首页> 外文期刊>Journal of Behavioral and Brain Science >A Modification of the Relative Weightings of Symptoms Utilizing a Logistic Function to Enhance the Linearity of the Brief Psychiatric Rating Scale: A Retrospective Analysis
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A Modification of the Relative Weightings of Symptoms Utilizing a Logistic Function to Enhance the Linearity of the Brief Psychiatric Rating Scale: A Retrospective Analysis

机译：运用Logistic函数改进症状的相对权重以增强简短精神病学评定量表的线性：一项回顾性分析

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Introduction: Although the Brief Psychiatric Rating Scale (BPRS) is widely used for evaluating patients with schizophrenia, the meaning of the weights of the individual symptoms is ambiguous. The aims of the study were 1) to investigate whether the modification of relative weights of items of the BPRS is able to enhance its correlation with the Clinical Global Impression-Schizophrenia scale (CGI-SCH) and 2) to construct a potential modified BPRS. Methods: We evaluated 200 schizophrenia patients using the BPRS and the CGI-SCH and drew the scatter plot distributions of the two scales. Next, univariate regression for the CGI-SCH using individual symptoms of the BPRS was performed. Multivariate regression utilizing the ‘logistic function’ was then conducted to allocate marks to each item and Pearson’s r correlation coefficient and r-squared between the two scales were assessed. After that, we constructed an example of a potential modified BPRS. Results: With the scatter plot for the two scales, a logarithmic curve was obtained; this was described by [CGI-SCH] = 3.2248 × ln[18-item BPRS] – 7.2044 (p i” that could express the relative weights of individual symptoms. Subsequently, modification of point allocations according to “Pi” yielded a Pearson’s r of 0.8491 and an r-squared of 0.7718 (not changed) (both p < 0.001). An example of a potential modified BPRS was constructed. Conclusions: Within the limits of our data, the weightings of items of the BPRS improved the correlation of the BPRS with the CGI-SCH for evaluating schizophrenia.
机译：简介：尽管简明精神病评定量表（BPRS）被广泛用于评估精神分裂症患者，但各个症状的权重含义仍然不明确。研究的目的是1）研究BPRS项目相对权重的修改是否能够增强其与临床整体印象-精神分裂症量表（CGI-SCH）的相关性，以及2）构建潜在的修改后的BPRS。方法：我们使用BPRS和CGI-SCH评估了200位精神分裂症患者，并绘制了两个量表的散点图分布。接下来，使用BPRS的个别症状对CGI-SCH进行单变量回归。然后使用“逻辑函数”进行多元回归以将标记分配给每个项目，并评估了两个量表之间Pearson的r相关系数和r平方。之后，我们构造了一个潜在的修改后的BPRS示例。结果：使用两个标度的散点图，获得了对数曲线; [CGI-SCH] = 3.2248×ln [18个项目BPRS] – 7.2044（pi）可以描述各个症状的相对权重，然后按“ Pi”对点分配进行修改，得出皮尔逊r为结论：在我们的数据范围内，BPRS项的权重改善了BPRS项的相关性，得出0.8491且r平方为0.7718（不变）（均为p <0.001）（均p <0.001）。带有CGI-SCH的BPRS用于评估精神分裂症。

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