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首页> 外文期刊>Journal of atherosclerosis and thrombosis. >Validation of Circumferential Carotid Artery Strain as a Screening Tool for Subclinical Atherosclerosis
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Validation of Circumferential Carotid Artery Strain as a Screening Tool for Subclinical Atherosclerosis

机译：验证颈动脉周围应变作为亚临床动脉粥样硬化的筛查工具

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Aim: We evaluated the validity of circumferential carotid artery strain as a marker for subclinical atherosclerosis and its benefit in addition to carotid intima-media thickness (IMT) to detect high-risk groups. Methods: The study was a cross-sectional study. From April 2007 to July 2008, 1057 patients who had undergone both echocardiography and carotid ultrasonography were consecutively enrolled. Circumferential carotid strain was obtained from the ratio of change in circular length during the cardiac cycle. Results: As the number of risk factors for atherosclerosis increased from 0 to ≥4, circumferential strain decreased accordingly (5.1±2.1, 4.4±1.8, 3.8±1.6, 3.3±1.3, 3.1±1.3%, p 15%). Compared to patients with documented atherosclerotic disease, patients without known atherosclerotic disease showed significantly higher circumferential strain (3.25±1.30 vs. 4.18±1.89%, p 2 =61.0 from 42.4, p < 0.001), whereas β-stiffness did not have additive power ( p = 0.439). Conclusion: Circumferential strain can be used as a screening tool for subclinical atherosclerosis and may help detect subjects at increased risk for atherosclerotic disease.
机译：目的：我们评估了颈动脉周围动脉应变作为亚临床动脉粥样硬化的标志物的有效性及其对颈动脉内膜中膜厚度（IMT）的检测作用，以检测高危人群。方法：本研究为横断面研究。从2007年4月到2008年7月，连续接受了1057例同时接受了超声心动图和颈动脉超声检查的患者。从心动周期中圆形长度的变化比率获得颈动脉应变。结果：随着动脉粥样硬化危险因素的数量从0增加到≥4，圆周应变相应减少（5.1±2.1、4.4±1.8、3.8±1.6、3.3±1.3、3.1±1.3％，p 15％）。与有记录的动脉粥样硬化疾病的患者相比，没有已知的动脉粥样硬化疾病的患者表现出明显更高的周向应变（3.25±1.30比4.18±1.89％，p 2 ＝ 61.0，从42.4，p <0.001），而β-刚度确实没有附加功率（p = 0.439）。结论：周向应变可作为亚临床动脉粥样硬化的筛查工具，并可帮助发现罹患动脉粥样硬化疾病风险增加的受试者。

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