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首页> 外文期刊>Journal of Cachexia, Sarcopenia and Muscle >Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study
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Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study

机译：与老年人骨骼肌质量，少肌症和少肌症肥胖相关的因素：一项多大陆研究

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Abstract Background The aim of this study was to evaluate the factors associated with low skeletal muscle mass (SMM), sarcopenia, and sarcopenic obesity using nationally representative samples of people aged ?￠???￥65 years from diverse geographical regions of the world. Methods Data were available for 18 363 people aged ?￠???￥65 years who participated in the Collaborative Research on Ageing in Europe survey conducted in Finland, Poland, and Spain, and the World Health Organization Study on global AGEing and adult health survey conducted in China, Ghana, India, Mexico, Russia, and South Africa, between 2007 and 2012. A skeletal muscle mass index (SMI) was created to reflect SMM. SMM, SMI, and percent body fat (%BF) were calculated with specific indirect population formulas. These estimates were based on age, sex, weight, height, and race. Sarcopenia and sarcopenic obesity were defined with specific cut-offs. Results The prevalence of sarcopenia ranged from 12.6% (Poland) to 17.5% (India), and that of sarcopenic obesity ranged from 1.3% (India) to 11.0% (Spain). Higher %BF was associated with lower SMM in all countries, and with sarcopenia in five countries ( p < 0.001). Compared to high levels of physical activity, low levels were related with higher odds for sarcopenia [OR 1.36 (95%CI 1.11?￠????1.67)] and sarcopenic obesity [OR 1.80 (95%CI 1.23?￠????2.64)] in the overall sample. Also, a dose-dependent association between higher numbers of chronic diseases and sarcopenic obesity was observed. Conclusions Physical activity and body composition changes such as high %BF are key factors for the prevention of sarcopenia syndrome.
机译：摘要背景本研究的目的是使用来自世界各地的65岁以上的全国代表性样本来评估与低骨骼肌质量（SMM），肌肉减少症和肌肉减少症相关的因素。方法收集了18363名年龄在65岁以上，参与芬兰，波兰和西班牙的“欧洲老龄化合作研究”调查以及世界卫生组织关于全球老龄化和成人健康调查的人的数据。该活动于2007年至2012年在中国，加纳，印度，墨西哥，俄罗斯和南非进行。骨骼肌质量指数（SMI）的建立反映了SMM。 SMM，SMI和身体脂肪百分比（％BF）是通过特定的间接种群公式计算得出的。这些估算是基于年龄，性别，体重，身高和种族的。肌肉减少症和肌肉减少症肥胖症有特定的临界值。结果少肌症的患病率从12.6％（波兰）至17.5％（印度），少肌症肥胖症的患病率在1.3％（印度）至11.0％（西班牙）之间。在所有国家，％BF升高与SMM降低有关，在五个国家与肌肉减少症相关（p <0.001）。与高水平的体育活动相比，低水平的运动与少肌症[OR 1.36（95％CI1.11≥1.67）]和少肌症的肥胖[OR 1.80（95％CI1.23≥1.17）有关。 ？2.64）]。另外，观察到更高数量的慢性疾病和少肌症肥胖之间的剂量依赖性关联。结论体育活动和身体成分的变化（例如高BF）是预防少肌症候群的关键因素。

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