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首页> 外文期刊>Journal of Biomedical Science and Engineering >Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement
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Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

机译：α-磷酸三钙/铝酸钙复合骨水泥的研制与表征

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Calcium phosphate cements have received much attention in recent decades owing to their biocompatibility, in situ handling, and shaping abilities. However, their low initial mechanical strength is still a major limitation. On the other hand, calcium aluminate cements (CACs) set fast and have a high initial strength and good corrosion resistance in contact with body fluids, making them excellent dental restorative materials. Therefore, the chemical, mechanical and biological properties of new-TCP/CA cement after aging in simulated body fluid (SBF) were investigated. The results indicated that the composites have setting times not appropriated for immediate applications and have degradation rates higher than those of the traditional CPCs. Moreover, the compressive strength of composite was lower than 5MPa and did not increase with SBF immersion. However, the α-TCP/CA composites showed a higher bioactivity at early stages and were not only more biocompatible but also more noncytotoxic.
机译：磷酸钙水泥由于其生物相容性，原位处理和成型能力而在近几十年受到了广泛的关注。但是，它们的低初始机械强度仍然是主要限制。另一方面，铝酸钙水泥（CAC）凝固快，与体液接触时具有较高的初始强度和良好的耐腐蚀性，使其成为极好的牙齿修复材料。因此，研究了新型TCP / CA水泥在模拟体液（SBF）中老化后的化学，机械和生物学特性。结果表明，该复合材料的固化时间不适合立即使用，并且降解率高于传统的CPC。而且，复合材料的抗压强度低于5MPa，并且随着SBF的浸入而没有增加。然而，α-TCP/ CA复合材料在早期显示出更高的生物活性，不仅具有更高的生物相容性，而且还具有更高的无细胞毒性。

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