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首页> 外文期刊>Journal of Addiction >Correlates and Consequences of Opioid Misuse among High-Risk Young Adults
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Correlates and Consequences of Opioid Misuse among High-Risk Young Adults

机译：高风险年轻成年人中阿片类药物滥用的相关性和后果

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Background. Prescription opioids are the most frequently misused class of prescription drug among young adults aged 18–25, yet trajectories of opioid misuse and escalation are understudied. We sought to model opioid misuse patterns and relationships between opioid misuse, sociodemographic factors, and other substance uses. Methods. Participants were 575 young adults age 16–25 who had misused opioids in the last 90 days. Latent class analysis was performed with models based on years of misuse, recency of misuse, and alternate modes of administration within the past 12 months, 3 months, and 30 days. Results. Four latent classes emerged that were differentially associated with heroin, cocaine, and methamphetamine use, tranquilizer misuse, daily opioid misuse, and opioid withdrawal. Alternate modes of administering opioids were associated with increased risk for these outcomes. Sociodemographic factors, homelessness, prescription history, and history of parental drug use were significantly associated with riskier opioid misuse trajectories. Conclusion. Young adults who reported more debilitating experiences as children and adolescents misused opioids longer and engaged in higher risk alternate modes of administering opioids. Data on decisions both to use and to alter a drug’s form can be combined to describe patterns of misuse over time and predict important risk behaviors.
机译：背景。在18至25岁的年轻人中，处方阿片类药物是最常被滥用的处方药类别，但对阿片类药物滥用和升级的轨迹仍未进行研究。我们试图对阿片类药物滥用模式以及阿片类药物滥用，社会人口统计学因素和其他物质用途之间的关系进行建模。方法。参与者为575名16-25岁的年轻人，他们在过去90天内滥用了阿片类药物。在过去12个月，3个月和30天内，使用了基于滥用年限，滥用率近来以及其他给药方式的模型进行了潜在类别分析。结果。出现了四个潜在类别，分别与海洛因，可卡因和甲基苯丙胺的使用，镇静剂的滥用，每日阿片类药物的滥用和阿片类药物的撤离有关。服用阿片类药物的其他方式与这些结局的风险增加相关。社会人口统计学因素，无家可归者，处方史和父母吸毒史与高风险的阿片类药物滥用轨迹密切相关。结论。随着儿童和青少年滥用阿片类药物的时间更长，并报告了服用阿片类药物的高风险替代方式，年轻人报告了更多的使人虚弱的经历。有关使用和更改药物形式的决定的数据可以组合起来描述随时间推移的滥用方式并预测重要的风险行为。

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