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首页> 外文期刊>Journal of Cancer Research and Treatment >Decoding the Ice-Water Energy Paradox in the DW-MRI Phantom for Tumors: Targeting Thermodynamics, Kinetic and Structural Molecular Mechanisms Commentary
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Decoding the Ice-Water Energy Paradox in the DW-MRI Phantom for Tumors: Targeting Thermodynamics, Kinetic and Structural Molecular Mechanisms Commentary

机译：解码肿瘤的DW-MRI幻象中的冰水能悖论：靶向热力学，动力学和结构分子机理评论

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摘要

Diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) are diagnostic tools widely used to detect solid tumors and monitor therapy response. The ice-water calibration phantom has led to more accurate and reproducible DWI and ADC diagnostics by reducing intra- and inter-vendor dispersion, independent of field intensity (1.5 - 3 Tesla). The ice-water calibration phantom method is based on the idea of thermal equilibrium. The discovery of exclusion zone (EZ) may deeply change such understanding. This paper highlights how thermodynamic, structural and kinetic results of the EZ paradigm may help to explain the ice-water energy paradox and cement our understanding of the ice-water phantom and its application in the diagnosis of solid tumors and other complex diseases.
机译：弥散加权成像（DWI）和表观弥散系数（ADC）是广泛用于检测实体瘤和监测治疗反应的诊断工具。冰水校准模型通过减少供应商之间和供应商之间的离散（与场强无关）（1.5-3 Tesla），已导致更准确，可重复的DWI和ADC诊断。冰水校准体模法基于热平衡的思想。禁区（EZ）的发现可能会深刻改变这种认识。本文着重介绍了EZ范式的热力学，结构和动力学结果如何有助于解释冰水能悖论，并巩固了我们对冰水体模的理解及其在实体瘤和其他复杂疾病诊断中的应用。

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