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首页> 外文期刊>Journal of Cardiovascular Disease Research >Transient Stress Lymphocytosis in Cardiac Emergencies: A Clinicopathological Study of Under-recognized Entity at a Tertiary Care Cardiology Institute in North India
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Transient Stress Lymphocytosis in Cardiac Emergencies: A Clinicopathological Study of Under-recognized Entity at a Tertiary Care Cardiology Institute in North India

机译：心脏紧急情况中的瞬时应激淋巴细胞增多：北印度三级心脏病学研究所未充分认识的实体的临床病理研究

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Background: Transient stress lymphocytosis is an under recognized acute self limiting entity characterized by absolute lymphocyte count ALC > 4x109/Lt , frequently seen in cardiac and obstetrical emergencies, nonsurgical traumas, epilepsy etc. this study aims to analyzed the clinic-pathological features of the patients of TSL in a tertiary care Cardiology institute in North India. Methods and Results: A total 142 cases were evaluated with a follow up of 15 days detail clinical history, examination finding, biochemical and hematological investigations and where ever possible the immunophenotypic data were analyzed and in 122 cases ALC returned to normal level followed by proportionate increase in neutrophil and platelet count. On immunophenotyping there was increase in all subset of lymphocyte including T cell, B cell and NK cell. Conclusion: Contrary to the expected neutrophilic response, a few acute stress full conditions are known to be associated with absolute lymphocytosis that is transient type and most often ignored by the treating clinician as many time in subsequent investigations the ALC was found to be normal. Usually this condition is associated with poor outcome.
机译：背景：短暂应激淋巴细胞增多症是一种未被认可的急性自我限制实体，其特征是绝对淋巴细胞计数ALC> 4x109 / Lt，常见于心脏和产科急诊，非手术创伤，癫痫等。本研究旨在分析该患者的临床病理特征印度北部三级心脏病研究所的TSL患者。方法和结果：对总共142例患者进行了评估，并随访了15天的详细临床病史，检查结果，生化和血液学检查，并在可能的情况下分析了免疫表型数据，在122例中，ALC恢复至正常水平，然后按比例增加中性粒细胞和血小板计数。在免疫表型分析中，淋巴细胞的所有子集（包括T细胞，B细胞和NK细胞）均增加。结论：与预期的嗜中性粒细胞反应相反，一些急性应激完全病与绝对淋巴细胞增多有关，是绝对类型，是暂时性的，在随后的研究中被ALC认为是正常的，在很多时候被治疗的临床医生常常忽略。通常，这种情况与不良的预后有关。

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