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首页> 外文期刊>Journal of Cardiovascular Disease Research >Association between Myocardial Infarction and Dermatoglyphics: A Cross-Sectional Study
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Association between Myocardial Infarction and Dermatoglyphics: A Cross-Sectional Study

机译：心肌梗死与皮肤象形文字之间的关联：跨领域研究

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Background: Myocardial infarction (MI) is a multifactorial and polygenic cardiovascular disease with high mortality rate. Early diagnosis could help in precautionary measures and change in life style. Many studies used dermatoglyphics as noninvasive technique to predict the incidence of genetic diseases. Here, we tried to assess the association of dermatoglyphic pattern between MI and controls. Methods: We investigated dermatoglyphic patterns among 800 participants (n=400 MI cases and n=400 control groups) representing South Indian population. Patients with MI were compared with control groups who did not have any history of MI. Results: Showed higher frequency whorls in MI patients and loops in control group (p<0.001). The study showed significant difference in distribution of whorl (OR = 0.298, 95%CI=0.223- 0.399, p=0.0001), loop (OR = 3.537, 95%CI=2.639-4.741, p=0.0001), arch (OR = 0.545, 95%CI=0.405-0.733, p=0.0001). Further, mean values of A-B ridge count (OR = 1.421, 95%CI=1.167-1.731, P=0.0001) of MI and control groups were significant (p<0.05). Conclusion: The present study showed that there is an association between dermatoglyphic patterns and MI cases. Further, findings suggest that dermatoglyphic patterns may contribute to etiology of early prediction of MI.
机译：背景：心肌梗塞（MI）是一种多因素多基因心血管疾病，死亡率高。早期诊断可能有助于采取预防措施并改变生活方式。许多研究使用皮纹作为非侵入性技术来预测遗传疾病的发病率。在这里，我们试图评估MI和控件之间的皮肤雕刻模式的关联。方法：我们调查了代表南印度人口的800名参与者（n = 400 MI病例和n = 400对照组）的皮肤形态学模式。将MI患者与没有任何MI历史的对照组进行比较。结果：在MI患者中显示出较高的螺纹轮转频率，而在对照组中则出现回旋（p <0.001）。研究显示轮（OR = 0.298，95％CI = 0.223-0.399，p = 0.0001），环（OR = 3.537，95％CI = 2.639-4.741，p = 0.0001），弓形（OR = 0.545，95％CI ＝ 0.405-0.733，p ＝ 0.0001）。此外，MI组和对照组的A-B脊计数平均值（OR = 1.421，95％CI = 1.167-1.731，P = 0.0001）显着（p <0.05）。结论：本研究表明，皮肤形态学特征与心肌梗死有关联。此外，研究结果表明，皮肤雕刻模式可能有助于早期预测MI的病因。

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