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The “Dead-End Tract” and Its Role in Arrhythmogenesis

机译:“死胡同”及其在心律失常中的作用

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Idiopathic outflow tract ventricular arrhythmias (VAs) represent a significant proportion of all VAs. The mechanism is thought to be catecholamine-mediated delayed after depolarizations and triggered activity, although other etiologies should be considered. In the adult cardiac conduction system it has been demonstrated that sometimes an embryonic branch, the so-called “dead-end tract”, persists beyond the bifurcation of the right and left bundle branch (LBB). Several findings suggest an involvement of this tract in idiopathic VAs (IVAs). The aim of this review is to summarize our current knowledge and the possible clinical significance of this tract.
机译:特发性流出道室性心律失常(VA)占所有VA的很大比例。尽管应考虑其他病因,但该机制被认为是儿茶酚胺介导的去极化和触发活性后延迟。在成年心脏传导系统中,已经证明有时胚胎分支,即所谓的“死末束”,会持续延伸超过左右束支(LBB)的分支。几个发现表明,该管道与特发性VA(IVA)有关。这篇综述的目的是总结我们目前的知识以及该道可能的临床意义。

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