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首页> 外文期刊>Journal of Clinical Medicine Research >Prevalence of Metabolic Syndrome and Its Clinical and Angiographic Profile in Patients With Naive Acute Coronary Syndrome in North Indian Population
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Prevalence of Metabolic Syndrome and Its Clinical and Angiographic Profile in Patients With Naive Acute Coronary Syndrome in North Indian Population

机译：北印度人群天真的急性冠脉综合征患者代谢综合征的患病率及其临床和血管造影资料

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Background: Data of isolated metabolic syndrome as risk factor in patients presenting with acute coronary syndrome (ACS) especially in context to Indian subcontinent are sparse. Therefore, we studied the prevalence of metabolic syndrome (MetS), and its clinical and angiographic profile in naive ACS patients in North Indian population.Methods: A single-center, prospective, observational study of 324 patients was conducted at LPS Institute of Cardiology, G.S.V.M. Medical College, Kanpur, India with newly diagnosed ACS patients with MetS, as per modified NCEP-ATP III criteria. They were divided into two groups with and without MetS, and their clinical and angiographic profiles were studied.Results: Prevalence of MetS in our study was 37.65%. Patients with MetS were significantly older than without MetS (60.3 ± 8.4 vs. 57.6 ± 7.9), and had females preponderance (35.24% vs. 24.25%), less tobacco abuse (30.32% vs. 42.57%), more non-ST-segment elevation ACS (58.19% vs. 36.14%), less ST-segment elevation myocardial infarction (STEMI) (41.80% vs. 63.86%), more cardiogenic shock (27.04% vs. 17.32%), recurrent ischemia (14.75% vs. 7.42%) and on angiogram, lesser single vessel disease (21.13% vs. 53.96%), more double vessel disease (39.34 vs. 24.26%), triple vessel disease (19.67% vs. 10.39%), left main (13.11% vs. 4.45%) and complex coronary lesions (tubular 40.98% vs. 31.68%; diffuse 26.23% vs. 18.32%). However, there was a trend of lower but insignificant mortality with MetS (5.44% vs. 6.55%).Conclusion: There was high prevalence of MetS among patients with ACS in North Indian population with more advanced coronary artery disease. To the best of our knowledge, this is the first study from North India documenting clinical and angiographic profile of patients with MetS and ACS.J Clin Med Res. 2016;8(9):667-673doi: http://dx.doi.org/10.14740/jocmr2655w
机译：背景：在患有急性冠状动脉综合征（ACS）的患者中，特别是在印度次大陆地区，孤立代谢综合征作为危险因素的数据很少。因此，我们研究了北印度裔天真的ACS患者的代谢综合征（MetS）的患病率及其临床和血管造影情况。方法：LPS心脏病研究所对324例患者进行了单中心，前瞻性和观察性研究， GSVM根据修订的NCEP-ATP III标准，印度坎普尔医学院拥有新诊断的ACS的MetS患者。将他们分为有和没有MetS的两组，并对其临床和血管造影资料进行研究。结果：本研究中MetS的患病率为37.65％。患有MetS的患者比没有MetS的患者显着年龄更大（60.3±8.4 vs. 57.6±7.9），女性占优势（35.24％vs. 24.25％），吸烟少（30.32％vs. 42.57％），非ST-分段抬高型ACS（58.19％对36.14％），ST段抬高型心肌梗死（STEMI）较少（41.80％对63.86％），心源性休克较多（27.04％对17.32％），复发性缺血（14.75％vs. 7.42％）和血管造影照片显示，单支血管病变较少（21.13％对53.96％），双支血管疾病较多（39.34对24.26％），三支血管疾病（19.67％对10.39％），左主干疾病（13.11％对4.45％）和复杂的冠状动脉病变（肾小管分别为40.98％和31.68％;弥漫性26.23％和18.32％）。然而，MetS的死亡率却有降低但微不足道的趋势（5.44％vs. 6.55％）。结论：在印度北部患有冠心病的晚期人群中，ACS患者的MetS患病率较高。据我们所知，这是来自北印度的第一项研究，记录了MetS和ACS患者的临床和血管造影情况。JClin Med Res。 2016; 8（9）：667-673doi：http://dx.doi.org/10.14740/jocmr2655w

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