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首页> 外文期刊>Journal of Clinical Medicine Research >Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation
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Bi-Luminal Mitral Valve: Incidence, Clinical Features, Associated Anomaly and Echocardiographic Evaluation

机译：双肺二尖瓣：发病率，临床特征，相关异常和超声心动图评估

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Objective: The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt.Methods: Twenty-eight patients with DOMV were diagnosed by transthoracic echocardiography (TTE) in a retrospective review of 52,256 echocardiographic studies in 45,898 patients performed between 2000 and 2015.Results: The mean age was 20.1 years (15 - 34 years) with female preponderance (M/F: 1:1.8). Dyspnea and diastolic murmur were the most common symptoms found in 19 (67.8%) and 19 (67.8%) of patients, respectively. Normal sinus rhythm was the most common electrocardiographic finding. Twenty-five (89%) patients had complete bridge, while three (11%) had incomplete bridge type of DOMV. Twenty-one (75%) had severe mitral stenosis (MS) including severe tricuspid regurgitation (n = 13, 61%), ventricular septal defect (VSD, n = 3, 14%), complete endocardial cushion defect (ECD, n = 3, 14%), and mild to moderate mitral regurgitation (MR) (n = 2, 11%), moderate MS and moderate MR were found in four (16%) patients among complete bridge type of DOMV, while all patients with incomplete bridge type had severe MS and patent ductus arteriosus (PDA) as associated lesions. Overall, 24 (85%) had severe and four (15%) had moderate MS.Conclusions: DOMV as a cause of symptomatic mitral valve disease was seen in young and middle-aged patients with estimated incidence of 0.06%. Dyspnea and diastolic murmur were the most common symptoms. Mostly, it was an isolated anomaly but in majority, associated with VSD, complete ECD and PDA. TTE examination is a reliable and sufficient means of diagnosing DOMV and determining its type.J Clin Med Res. 2016;8(12):893-898doi: http://dx.doi.org/10.14740/jocmr2790w
机译：目的：本研究旨在了解疑似二尖瓣疾病，连续性杂音或左心房狭窄的患者的双腔二尖瓣（也称为双孔二尖瓣或DOMV）的发生率，临床特征，相关异常和超声心动图评估方法：回顾性回顾了2000年至2015年间对45,898例患者进行的52,256例超声心动图研究，通过经胸超声心动图（TTE）诊断为28例DOMV患者。结果：平均年龄为20.1岁（15- 34岁），女性占优势（男/女：1：1.8）。呼吸困难和舒张期杂音是分别在19（67.8％）和19（67.8％）患者中发现的最常见症状。正常窦性心律是最常见的心电图表现。 25例（89％）的患者具有完整的桥，而3例（11％）的DOMV桥类型不完整。 21名（75％）患有严重的二尖瓣狭窄（MS），包括严重的三尖瓣关闭不全（n = 13、61％），室间隔缺损（VSD，n = 3、14％），完全的心内膜垫缺损（ECD，n = 3％，14％）和轻度至中度二尖瓣关闭不全（MR）（n = 2、11％），中度MS和中度MR在完全过桥型DOMV中的四（16％）例患者中发现，而所有患者均不完全桥型伴有严重的MS和动脉导管未闭（PDA）作为相关病变。总体而言，严重的有24位（85％），中度的MS有4位（15％）。结论：在年轻和中年患者中发现DOMV是症状性二尖瓣疾病的病因，估计发病率为0.06％。呼吸困难和舒张期杂音是最常见的症状。通常，这是一个孤立的异常，但大多数情况下与VSD，完整的ECD和PDA有关。 TTE检查是诊断DOMV并确定其类型的可靠且充分的方法。JClin Med Res。 2016; 8（12）：893-898doi：http://dx.doi.org/10.14740/jocmr2790w

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