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首页> 外文期刊>Journal of Clinical Medicine Research >Sleep Quality in Rheumatoid Arthritis: Relationship Between the Disease Severity, Depression, Functional Status and the Quality of Life
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Sleep Quality in Rheumatoid Arthritis: Relationship Between the Disease Severity, Depression, Functional Status and the Quality of Life

机译：类风湿关节炎的睡眠质量：疾病严重程度，抑郁，功能状态和生活质量之间的关系

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Background: The aim of this study was to evaluate sleep quality and the related variables in patients with rheumatoid arthritis (RA). Methods: Ninety-four patients diagnosed with RA and fifty two healthy controls were enrolled in the study. Disease activity was assessed through the Disease Activity Score (DAS) 28 scale. All patients were assessed using the Rheumatoid Arthritis Quality of Life and Health Assessment Questionnaire scales, together with the Beck Depression Inventory. Radiological damage was calculated with the modified Larsen method. The Pittsburgh Sleep Quality Index (PSQI) was used for the evaluation of the sleep disturbance. Results: The patients with RA had significantly higher scores in the subjective sleep quality, sleep latency, habitual sleep efficiency, sleep disturbance domains and the total PSQI score compared to the healthy control group. According to the results of Spearman’s analysis, there was a significantly correlation between the age, disease activity, CRP, pain, fatigue, depression, functional disability, quality of life, radiological damage, menopause status, duration of morning stiffness, ESR levels and the sleep disturbance. The logistic regression analysis indicated that depression and DAS 28 scores were predictors for poor sleep quality. Conclusion: The sleep quality is disturbed in patients with RA. The poor sleep quality is especially associated with the disease activity and depression.J Clin Med Res. 2014;6(1):44-52doi: http://dx.doi.org/10.4021/jocmr1648w
机译：背景：本研究的目的是评估类风湿关节炎（RA）患者的睡眠质量和相关变量。方法：本研究纳入了94例确诊为RA的患者和52名健康对照者。通过疾病活动评分（DAS）28量表评估疾病活动。使用类风湿关节炎生活质量和健康评估问卷量表以及贝克抑郁量表对所有患者进行评估。用改良的拉森方法计算放射损伤。匹兹堡睡眠质量指数（PSQI）用于评估睡眠障碍。结果：与健康对照组相比，RA患者在主观睡眠质量，睡眠潜伏期，习惯性睡眠效率，睡眠障碍域和总PSQI评分方面得分明显更高。根据Spearman的分析结果，年龄，疾病活动，CRP，疼痛，疲劳，抑郁，功能障碍，生活质量，放射线损伤，更年期状态，早晨僵硬持续时间，ESR水平和血脂水平之间存在显着相关性。睡眠障碍。 Logistic回归分析表明，抑郁和DAS 28得分是不良睡眠质量的预测因素。结论：RA患者的睡眠质量受到影响。睡眠质量差尤其与疾病活动和抑郁有关。 2014; 6（1）：44-52doi：http://dx.doi.org/10.4021/jocmr1648w

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