Near Misdiagnosis of Glioblastoma as Primary Central Nervous System Lymphoma

Vijaya Raj Bhatt; Rajesh Shrestha; Nicole Shonka; R. Gregory Bociek

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Near Misdiagnosis of Glioblastoma as Primary Central Nervous System Lymphoma

机译：胶质母细胞瘤被误诊为原发性中枢神经系统淋巴瘤

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Primary central nervous system (CNS) lymphoma, most frequently a diffuse large B-cell lymphoma, is a rare aggressive lymphoma confined to the CNS, thus requiring differentiation from other brain malignancies such as glioblastoma. Although stereotactic biopsy can confirm the diagnosis, this is invasive, not always feasible and can be inconclusive after steroid use. Hence, cranial magnetic resonance imaging (MRI) with contrast and cerebrospinal fluid analysis are frequently used to make a prompt diagnosis. We report a case of a woman with two brain masses who presented unique diagnostic challenge.J Clin Med Res. 2014;6(4):299-301doi: http://dx.doi.org/10.14740/jocmr1846w

机译：原发性中枢神经系统（CNS）淋巴瘤，最常见的是弥漫性大B细胞淋巴瘤，是一种局限在CNS中的罕见侵袭性淋巴瘤，因此需要与其他脑恶性肿瘤（例如成胶质细胞瘤）区分开。尽管立体定向活检可以确诊，但是这是侵入性的，并不总是可行的，在类固醇使用后可能不确定。因此，经常使用具有对比和脑脊液分析的颅骨磁共振成像（MRI）进行快速诊断。我们报道了一例有两个脑部肿块的妇女，这些妇女提出了独特的诊断挑战。JClin Med Res。 2014; 6（4）：299-301doi：http://dx.doi.org/10.14740/jocmr1846w

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《Journal of Clinical Medicine Research》 |2014年第4期|共3页
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Vijaya Raj Bhatt; Rajesh Shrestha; Nicole Shonka; R. Gregory Bociek;
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1. Primary central nervous system lymphoma can be histologically diagnosed after previous corticosteroid use: a pilot study to determine whether corticosteroids prevent the diagnosis of primary central nervous system lymphoma. [J] . Porter AB, Giannini C, Kaufmann T, Annals of neurology . 2008,第5期

机译：原发性中枢神经系统淋巴瘤可在先前使用皮质类固醇激素后进行组织学诊断：一项初步研究，确定皮质类固醇激素是否可预防原发性中枢神经系统淋巴瘤的诊断。
2. MRI as a diagnostic biomarker for differentiating primary central nervous system lymphoma from glioblastoma: A systematic review and meta‐analysis [J] . Suh Chong Hyun, Kim Ho Sung, Jung Seung Chai, Journal of magnetic resonance imaging: JMRI . 2019,第2期

机译：MRI作为诊断生物标志物，用于区分胶质母细胞瘤的初级中枢神经系统淋巴瘤：系统评价和荟萃分析
3. Diagnostic performance of DWI for differentiating primary central nervous system lymphoma from glioblastoma: a systematic review and meta-analysis [J] . Lu Xiaoyang, Xu Weilin, Wei Yuyu, Neurological sciences . 2019,第5期

机译：DWI对胶质细胞瘤微分中枢神经系统淋巴瘤的诊断性能：系统评价和荟萃分析
4. Mutational profile of Diffuse Large B-cell Lymphoma with central nervous system relapse: analysis of CBioPortal for Cancer Genomics database [C] . Elena Voropaeva, Olga Beresina, Tatyana Pospelova, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：弥漫性大B细胞淋巴瘤与中枢神经系统复发的突变特征：用于癌症基因组学数据库的CBioPortal分析
5. Utility of apparent diffusion coefficients in the evaluation of primary central nervous system lymphoma. [D] . Gilbert, John Webster. 2012

机译：表观扩散系数在原发性中枢神经系统淋巴瘤评估中的应用。
6. Near Misdiagnosis of Glioblastoma as Primary Central Nervous System Lymphoma [O] . Vijaya Raj Bhatt, Rajesh Shrestha, Nicole Shonka, 2014

机译：胶质母细胞瘤被误诊为原发性中枢神经系统淋巴瘤
7. Near Misdiagnosis of Glioblastoma as Primary Central Nervous System Lymphoma [O] . 2014

机译：近乎味噌母细胞瘤的误诊为原发性神经系统淋巴瘤

Near Misdiagnosis of Glioblastoma as Primary Central Nervous System Lymphoma

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