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首页> 外文期刊>Journal of Clinical Medicine Research >Relationship of Clinical and Pathologic Nodal Staging in Locally Advanced Breast Cancer: Current Controversies in Daily Practice?
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Relationship of Clinical and Pathologic Nodal Staging in Locally Advanced Breast Cancer: Current Controversies in Daily Practice?

机译：局部晚期乳腺癌的临床和病理学淋巴结分期的关系：日常实践中的当前争议？

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Systemic neo-adjuvant therapy plays a primary role in the management of locally advanced breast cancer. Without having any negative effect in overall survival, induction chemotherapy potentially assures a surgery approach in unresectable disease or a conservative treatment in technically resectable disease and acts on a well-vascularized tumor bed, without the modifications induced by surgery. A specific issue has a central function in the neo-adjuvant setting: lymph nodes status. It still represents one of the strongest predictors of long-term prognosis in breast cancer. The discussion of regional radiation therapy should be a matter of debate, especially in a pathological complete response. Currently, the indication for radiotherapy is based on the clinical stage before the surgery, even for the irradiation of the loco-regional lymph nodes. Regardless of pathological down-staging, radiation therapy is accepted as standard adjuvant treatment in locally advanced breast cancer.J Clin Med Res. 2014;6(6):409-413doi: http://dx.doi.org/10.14740/jocmr1908w
机译：全身新辅助治疗在局部晚期乳腺癌的治疗中起主要作用。在不对总体存活率产生任何负面影响的情况下，诱导化学疗法可确保在无法切除的疾病中采用手术方法或在技术上可切除的疾病中采用保守治疗，并在血管良好的肿瘤床上起作用，而无需通过手术引起任何改变。在新辅助治疗中，一个特定的问题具有核心功能：淋巴结状态。它仍然代表着乳腺癌长期预后的最强预测指标之一。区域放射治疗的讨论应该是一个辩论的问题，尤其是在病理性完全反应中。目前，放射疗法的指征基于手术前的临床阶段，甚至局部区域淋巴结的照射也是如此。无论病理分期如何，放射治疗均被视为局部晚期乳腺癌的标准辅助治疗方法.J Clin Med Res。 2014; 6（6）：409-413doi：http://dx.doi.org/10.14740/jocmr1908w

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