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首页> 外文期刊>Journal of Clinical Medicine >Driving Cessation and Cognitive Dysfunction in Patients with Mild Cognitive Impairment
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Driving Cessation and Cognitive Dysfunction in Patients with Mild Cognitive Impairment

机译：轻度认知障碍患者的驾驶中止和认知功能障碍

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Although driving by adults with cognitive impairment is an important public health concern, little is known about the indicators of driving cessation in patients with mild cognitive impairment (MCI). We aimed to investigate the prevalence of driving cessation in patients with MCI and the predictive value of cognitive performances for driving cessation. Patients with MCI were recruited in the Seoul National University Bundang Hospital; they met following inclusion criteria. Age range of 51–80 years, Clinical Dementia Rating scale score of 0.5, and ever car drivers including former and current drivers. All participants underwent comprehensive standardized cognitive assessments and information on driving status was obtained via an interview using a systematic questionnaire. The median age of the 135 participants was 72 years, and 54 participants (40%) were women; 93 patients (68.9%) were current drivers and 42 (31.1%) were former drivers. In univariate analysis, former drivers showed poorer performances in digit span backward and categorical fluency tests than current drivers. In multivariate logistic regression analysis, a poor digit span backward test score was significantly related with driving cessation (odds ratio: 0.493, 95% confidence interval: 0.258–0.939). In patients with MCI, poor performance in the digit span backward test, which represents impaired working memory capacity, was associated with a higher probability of driving cessation.
机译：尽管有认知障碍的成年人开车是一个重要的公共卫生问题，但对于轻度认知障碍（MCI）患者停止驾驶的指标知之甚少。我们的目的是调查MCI患者中驾驶停止的患病率以及认知表现对驾驶停止的预测价值。首尔国立大学盆唐医院招募了MCI患者;他们符合以下入选标准。年龄范围为51-80岁，临床痴呆评定量表得分为0.5，并且曾经有汽车驾驶员，包括前任和现任驾驶员。所有参与者都接受了全面的标准化认知评估，并且通过使用系统问卷调查的方式获得了有关驾驶状态的信息。 135名参与者的中位年龄为72岁，其中54名参与者（占40％）是女性。目前的驾驶员为93名患者（68.9％），以前的驾驶员为42名（31.1％）。在单变量分析中，以前的驱动程序在数位后向和分类流畅性测试中的表现比当前的驱动程序差。在多元逻辑回归分析中，不良的数字跨度后测得分与驾驶终止显着相关（赔率：0.493，95％置信区间：0.258–0.939）。在患有MCI的患者中，数字跨度向后测试中的不良表现（代表工作记忆能力受损）与较高的驾驶戒断率相关。

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