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首页> 外文期刊>Journal of Clinical Medicine and Research >Comparative study of the effects of single and dual infections of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in peripheral blood lymphocytes of infected individuals in Ebonyi State, Nigeria
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Comparative study of the effects of single and dual infections of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in peripheral blood lymphocytes of infected individuals in Ebonyi State, Nigeria

机译：尼日利亚埃博尼州单次和双次感染人类免疫缺陷病毒（HIV）和乙型肝炎病毒（HBV）感染者外周血淋巴细胞的效果比较研究

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A total of 700 blood specimens of patients’ attending hematology units of Federal Medical Centre (FMC), Mile Four Hospital, Ebonyi State University Teaching Hospital (EBSUTH) Abakaliki, Mater Misericodia Hospital Afikpo and Private Medical Laboratory Units in Abakaliki town were serologically screened for the presence of human immunodeficiency virus, (HIV), and hepatitis virus and also assayed for absolute lymphocyte count using the improved neubeur chamber heamocytometric method. Fifty two (7.43%), ninety four (13.42%) and eight (1.14%) individuals were positive for HIV, HBV and HIV/ HBV infections respectively. The range of the mean lymphocyte counts for positive individual were 0.6 ± 0.06 - 0.84? ± 0.04 for HIV, 0.51 ± 0.17 - 0.7 ±? 0.11 for HBV and 0.35 ± 0.08 - 0.46 ± 0.18 for HIV / HBV x 109/L respectively. Individuals who were below 10 years of age were mostly affected by HIV (25.0%), HBV (25.0%) and HIV/ HBV (12.5%). Highest rate of multiple sexual partnerships (63.7%) occurred among the age group of 21 - 30 years. Statistical analysis (?2) showed significant relationship between HIV, HBV and HIV/ HBV infections with age. To aid clinical management, the variation of absolute lymphocyte counts may be a guide in monitoring the progression of the diseases.
机译：通过血清学筛查了联邦医学中心（FMC），英里四医院，埃邦尼州立大学教学医院（EBSUTH）Abakaliki，Mater Misericodia医院Afikpo和位于Abakaliki镇的私人医学实验室单位的血液科患者的700份血液样本人免疫缺陷病毒（HIV）和肝炎病毒的存在，并使用改良的神经小室血细胞计数法测定绝对淋巴细胞计数。分别有52名（7.43％），94名（13.42％）和8名（1.14％）的HIV，HBV和HIV / HBV感染阳性。阳性个体的平均淋巴细胞计数范围为0.6±0.06-0.84？ HIV±0.04，0.51±0.17-0.7±？ HBV为0.11，HIV / HBV x 109 / L为0.35±0.08-0.46±0.18。 10岁以下的个体主要受艾滋病毒（25.0％），乙肝病毒（25.0％）和艾滋病毒/乙肝病毒（12.5％）的影响。在21至30岁的年龄组中，多重性伴侣关系的发生率最高（63.7％）。统计分析（？2）显示，HIV，HBV和HIV / HBV感染与年龄之间存在显着关系。为了帮助临床管理，绝对淋巴细胞计数的变化可能是监测疾病进展的指南。

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