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首页> 外文期刊>Journal of Clinical Medicine Research >Laparoscopic Versus Open Colorectal Resection Within Fast Track Programs: An Update Meta-Analysis Based on Randomized Controlled Trials
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Laparoscopic Versus Open Colorectal Resection Within Fast Track Programs: An Update Meta-Analysis Based on Randomized Controlled Trials

机译:腹腔镜与开放性结直肠切除术在快速通道程序内:基于随机对照试验的更新Meta分析

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The objective of the study was to assess the safety and efficacy of laparoscopic colorectal surgery by comparing open operation within fast track (FT) programs. The Cochrane Library, PubMed, Embase and Chinese Biological Medicine Database were searched to identify all available randomized controlled trials (RCTs) comparing laparoscopic with open colorectal resection within FT programs. A total of seven RCTs were finally included, enrolling 714 patients with colorectal cancer: 373 patients underwent laparoscopic surgery and FT programs (laparoscopic/FT group) and 341 patients received open operation and FT programs (open/FT group). Postoperative hospital stay (weighted mean difference (WMD): 0.66; 95% CI: 0.27 - 1.04; P < 0.05), total hospital stay (WMD: 1.46; 95% CI: 0.40 - 2.51; P < 0.05) and overall complications (RR: 1.31; 95% CI: 1.12 - 1.54; P < 0.05) were significantly lower in laparoscopic/FT group than in open/FT group. However, no statistically significant differences on mortality (risk ratio (RR): 2.26; 95% CI: 0.62 - 8.22; P = 0.21), overall surgical complications (RR: 1.19; 95% CI: 0.94 - 1.51; P = 0.15) and readmission rates (RR: 1.33; 95% CI: 0.79 - 2.22; P = 0.28) were found between both groups. The laparoscopic colorectal surgery combined with FT programs shows high-level evidence on shortening postoperative and total hospital stay, reducing overall complications without compromising patients’ safety.J Clin Med Res. 2015;7(8):594-601doi: http://dx.doi.org/10.14740/jocmr2177w
机译:这项研究的目的是通过比较快速通道(FT)程序中的开放手术来评估腹腔镜结直肠癌手术的安全性和有效性。搜索Cochrane图书馆,PubMed,Embase和中国生物医学数据库,以鉴定所有可比较FT计划中腹腔镜与开放性结直肠切除术的随机对照试验(RCT)。最终共纳入7个RCT,招募了714例大肠癌患者:373例接受了腹腔镜手术和FT程序的患者(腹腔镜/ FT组)和341例接受了开放手术和FT程序的患者(开放/ FT组)。术后住院时间(加权平均差异(WMD):0.66; 95%CI:0.27-1.04; P <0.05),总住​​院时间(WMD:1.46; 95%CI:0.40-2.51; P <0.05)和总体并发症( RR:1.31; 95%CI:1.12-1.54; P <0.05)在腹腔镜/ FT组明显低于开放/ FT组。但是,在死亡率(风险比(RR):2.26; 95%CI:0.62-8.22; P = 0.21),总体手术并发症(RR:1.19; 95%CI:0.94-1.51; P = 0.15)方面,无统计学差异。两组之间的再入院率(RR:1.33; 95%CI:0.79-2.22; P = 0.28)。腹腔镜结直肠癌手术与FT程序相结合,显示出缩短术后和住院时间,减少总体并发症而不损害患者安全性的高水平证据。JClin Med Res。 2015; 7(8):594-601doi:http://dx.doi.org/10.14740/jocmr2177w

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