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首页> 外文期刊>Journal of Clinical Medicine and Research >Corneal biomechanical characteristics, intraocular pressure and central corneal thickness in patients with type 2 diabetes mellitus
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Corneal biomechanical characteristics, intraocular pressure and central corneal thickness in patients with type 2 diabetes mellitus

机译：2型糖尿病患者的角膜生物力学特征，眼压和中央角膜厚度

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To evaluate corneal biomechanical properties, intraocular pressure and central corneal thickness in type 2 diabetic patients by Ocular Response Analyzer (ORA), ORA measurements were performed on the 80 eyes of 40 diabetic patients (group I) and 80 eyes of 40 healthy people who served as the control group (group II). Corneal hysteresis (CH), corneal resistance factor (CRF), intraocular pressure (Goldmann correlated [IOPg], corneal compensated [IOPcc]) and central corneal thickness (CCT) values were determined by ORA. Mean age of patients with diabetic melitus (DM) and control groups were 51.8 ± 5.8 and 51.2 ± 7.1 years, respectively. Mean CH and CRF were 9.44 ± 0.62 versus 9.41 ± 0.50 (p=0.738) and 11.58 ± 0.60 versus 10.56 ± 0.50 (p<0.001), in groups I and II, respectively. Mean IOPg and IOPcc were 19.90 ± 3.35 mmHg versus 18.90 ± 2.56 mmHg (p=0.036) and 17.41 ± 2.57 mmHg versus 17.22 ± 2.66 mmHg (p=0.651) in groups I and II, respectively. Mean CCT’s were 548.02 ± 23.16 versus 521.92±31.60 (p<0.001) in groups I and II, respectively. Statistical analysis revealed significant differences for CRF, IOPg and CCT values between groups. CRF, IOPg and CCT values were altered in diabetics and these changes can be detected by ORA.?Further studies are required to establish the effects of type 2 diabetes on corneal biomechanical properties.
机译：为了通过眼反应分析仪（ORA）评估2型糖尿病患者的角膜生物力学特性，眼内压和角膜中央厚度，对40例糖尿病患者（第一组）的80眼和40例健康人的80眼进行了ORA测量作为对照组（第二组）。角膜滞后（CH），角膜抵抗因子（CRF），眼内压（Goldmann相关[IOPg]，角膜补偿[IOPcc]）和中央角膜厚度（CCT）值通过ORA确定。糖尿病组的平均年龄（DM）和对照组分别为51.8±5.8和51.2±7.1岁。 I组和II组的平均CH和CRF分别为9.44±0.62对9.41±0.50（p = 0.738）和11.58±0.60对10.56±0.50（p <0.001）。 I组和II组的平均IOPg和IOPcc分别为19.90±3.35 mmHg和18.90±2.56 mmHg（p = 0.036）和17.41±2.57 mmHg与17.22±2.66 mmHg（p = 0.651）。 I组和II组的平均CCT分别为548.02±23.16和521.92±31.60（p <0.001）。统计分析显示两组之间的CRF，IOPg和CCT值存在显着差异。糖尿病患者的CRF，IOPg和CCT值发生变化，这些变化可以通过ORA进行检测。需要进一步的研究来确定2型糖尿病对角膜生物力学特性的影响。

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