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A case report of renal Ewing sarcoma

机译:肾尤因肉瘤1例

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摘要

Primitive neuro-ectodermal tumors (PNETs) are seen mostly at central nervous system. Peripheral localizations are rare. PNETs are belong to Ewing sarcoma family. Ew-ing sarcoma has two subtypes as originated from bones or from another organ. Renal PNET is a very rare tumor. Peripherally localized PNETs originated from kidney, usu-ally found at young men, and have poor prognosis with aggressive behavior. A 28-year-old man referred to our clinic with left flank pain and gross hematuria. Radiologi-cal investigations yielded gross renal mass compatible with malignancy. Radical nephrectomy was performed. Histopathological diagnosis was PNET/Ewing sarcoma with findings of large and hyperchromatous nuclei, narrow cytoplasms, spindle shaped cells- but mostly rosette for-mation- and strong straining with CD99. Chemotherapy was given to the patient. At the end of the chemotherapy, there no recurrence was detected by radiological investi-gations
机译:原始神经外胚层肿瘤(PNET)大多见于中枢神经系统。外围定位很少。 PNET属于Ewing肉瘤家族。尤因肉瘤有两种亚型,起源于骨骼或另一器官。肾PNET是一种非常罕见的肿瘤。周围定位的PNET起源于肾脏,通常在年轻男性中发现,并且具有侵略性行为的预后较差。一名28岁的男子因左胁腹疼痛和严重血尿转诊到我们的诊所。放射学检查显示,总肾质量与恶性肿瘤相容。进行了根治性肾切除术。组织病理学诊断为PNET /尤文氏肉瘤,发现有大而高色的细胞核,狭窄的细胞质,纺锤形细胞(但多数为玫瑰花结形)以及CD99的强烈拉伤。对患者进行了化学疗法。化疗结束时,放射学检查未发现复发

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