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Nutrition for Sarcopenia

机译:肌肉减少症的营养

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Aging-related sarcopenia means that muscle mass, strength, and physical performance tend to decline with age, and malnutrition is associated with sarcopenia. Therefore, nutritional interventions may make an important contribution to prevent the development of sarcopenia. Here I reviewed published articles about the effects of nutritional factors on sarcopenia in elderly people. A growing body of evidence suggests that metabolic factors associated with obesity and diabetes induce the progression of sarcopenia. However, the effectiveness and safety of caloric restriction for sarcopenia remained unclear. Protein intake and physical activity are the main anabolic stimuli for muscle protein synthesis. As optimal dietary protein intake, 1.0 - 1.2 g/kg (body weight)/day with an optimal repartition over each daily meal or 25 - 30 g of high quality protein per meal were recommended to prevent sarcopenia, which was supported by some observational studies. Protein supplementation using cheese and milk protein, essential amino acids, leucine, beta-hydroxy-beta-methylbutyrate and vitamin D has been investigated as a potential supplement to improve muscle quality in sarcopenic elderly people.J Clin Med Res. 2015;7(12):926-931doi: http://dx.doi.org/10.14740/jocmr2361w
机译:与衰老相关的肌肉减少症意味着肌肉质量,力量和身体机能会随着年龄的增长而下降,营养不良与肌肉减少症有关。因此,营养干预可能对预防少肌症的发展做出重要贡献。在这里,我回顾了有关营养因素对老年人少肌症的影响的已发表文章。越来越多的证据表明,与肥胖症和糖尿病有关的代谢因子会导致肌肉减少症的发展。然而,热量减少对少肌症的有效性和安全性尚不清楚。蛋白质的摄入和身体活动是肌肉蛋白质合成的主要合成代谢刺激。作为最佳的饮食蛋白质摄入量,建议每天饮食中最佳分配1.0-1.2 g / kg(体重)/天或每餐25-30 g优质蛋白质,以防止肌肉减少症,这得到了一些观察性研究的支持。已经研究了使用奶酪和牛奶蛋白,必需氨基酸,亮氨酸,β-羟基-β-甲基丁酸酯和维生素D补充蛋白质作为改善肌肉减少症的老年人肌肉质量的潜在补充剂。JClin Med Res。 2015; 7(12):926-931doi:http://dx.doi.org/10.14740/jocmr2361w

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