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Use of imaging modalities and the effectiveness of radiation therapy on brain tumors in a tertiary hospital in Nigeria

机译：尼日利亚一家三级医院的影像学检查方法和脑肿瘤放射治疗的有效性

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Background: Brain neoplasia is of concern in our environment because there are no preventive measures or sufficient availability of definite treatment. With imaging, the disease can be detected and the treatment evaluated. Materials and Methods: In this retrospective study carried out at a tertiary hospital in Nigeria, diagnostic imaging modalities used for imaging brain tumors, the pattern of tumors identified at histology, and the response of brain neoplasia to radiation therapy were analyzed. Results: Out of the 147 patients included in the study, the mean age was 44.5 ± 2.3 years of age. For diagnostic imaging, 60% used only computed tomography (CT) scan, 24% used magnetic resonance imaging (MRI), while 16% used both CT scan and MRI. Histologically, primary tumors (54%) occurred more than metastasis (46%). Breast metastasis (33.3%) was the singular most common tumor, followed by astrocytoma (19%). For definitive management, almost half of the cases (49%) had radiotherapy alone. 25% had radiotherapy with surgery, 10% had both radiotherapy and chemotherapy while 16% had all three. Four weeks posttreatment, there was 78% positive response to therapy. Conclusion: In our environment, the radiological evaluation of brain tumors is often by CT scan, even though MRI offers better soft-tissue contrast. This may be ascribed to the relative affordability and availability of CT scan. Radiation therapy is effective in the treatment of brain tumors.
机译：背景：在我们的环境中，脑瘤的发展令人担忧，因为目前尚无预防措施或有足够的明确治疗方法。通过成像，可以检测出疾病并评估治疗方案。材料和方法：在尼日利亚三级医院进行的这项回顾性研究中，分析了用于对脑部肿瘤进行成像的诊断性成像方式，在组织学上确定的肿瘤模式以及对脑瘤对放射治疗的反应。结果：纳入研究的147例患者中，平均年龄为44.5±2.3岁。对于诊断成像，60％仅使用计算机断层扫描（CT）扫描，24％使用磁共振成像（MRI），而16％同时使用CT扫描和MRI。从组织学上看，原发肿瘤（54％）的发生率比转移灶（46％）多。乳腺癌转移灶（33.3％）是最常见的肿瘤，其次是星形细胞瘤（19％）。对于最终治疗，几乎一半的病例（49％）仅接受放射治疗。 25％的患者接受了手术放疗，10％的患者接受了放疗和化疗，而16％的患者同时接受了这三种治疗。治疗后四周，对治疗的阳性反应为78％。结论：在我们的环境中，即使MRI可以提供更好的软组织对比，也通常需要通过CT扫描对脑肿瘤进行放射学评估。这可能归因于CT扫描的相对负担能力和可用性。放射疗法对脑肿瘤有效。

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