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首页> 外文期刊>Journal of Cytology >Testicular embryonal carcinoma presenting as chest wall subcutaneous mass
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Testicular embryonal carcinoma presenting as chest wall subcutaneous mass

机译:表现为胸壁皮下包块的睾丸胚胎癌

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摘要

Embryonal carcinoma affects young males in the prime of life with a majority of these tumors already having metastasis at the time of diagnosis. Subcutaneous metastasis from embryonal carcinoma are very rare and often associated with wide spread disease and poor prognosis. We report a case of chest wall subcutaneous metastasis of embryonal carcinoma in a 27 year-old man that was the first presentation of the disease and was diagnosed on fine needle aspiration cytology (FNAC). Subsequent search led to the discovery of the primary in the testis. The cytomorphological features of embryonal carcinoma are quite distinctive and FNAC plays a vital role in early diagnosis. The criteria for diagnosis includes presence of cellular smears exhibiting disperse cells as well as cell aggregates forming microglandular patterns. Cells have large nuclei with prominent nucleoli and pale indistinct often vacuolated cytoplasm. Early diagnosis and treatment with platinum based chemotherapy in conjunction with radiotherapy and surgery have high cure rate.Keywords: Chest wall metastasis, embryonal carcinoma, fine needle aspiration cytology
机译:胚胎癌在青春期开始影响年轻男性,其中大多数肿瘤在诊断时已经转移。胚胎癌的皮下转移非常罕见,通常与疾病广泛传播和预后不良有关。我们报告了一名27岁男子的胚胎癌胸壁皮下转移的病例,这是该病的首次表现,经细针穿刺细胞学检查(FNAC)诊断。随后的搜索导致在睾丸中发现原发灶。胚胎癌的细胞形态特征十分独特,FNAC在早期诊断中起着至关重要的作用。诊断标准包括细胞涂片表现出分散的细胞以及形成微腺模式的细胞聚集体。细胞核大,核仁明显,苍白模糊,常呈空泡状。铂类化学疗法结合放疗和手术的早期诊断和治疗具有较高的治愈率。关键词:胸壁转移,胚胎癌,细针穿刺细胞学

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