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The Efficacy of Green Tea Chewing Gum on Gingival Inflammation

机译:绿茶口香糖对牙龈炎症的功效

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Statement of the Problem: According to previous studies, the components of green tea extracts can inhibit the growth of a wide range of gram-pos-itive and -negative bacterial species and might be useful in controlling oral infections. Purpose: The aim of this study was to determine the effect of green tea chewing gum on the rate of plaque and gingival inflammation in subjects with gingivitis. Materials and Method: In this double-blind randomize controlled clinical trial, 45 patients with generalized marginal gingivitis were selected and divided into two groups of green tea (23) and placebo (22) chewing gum. The patients chewed two gums for 15 minutes daily for three weeks. Sulcus bleeding index (SBI) and approximal plaque index (API) were studied at the baseline, 7 and 21 days later. Saliva sampling was conducted before and after 21 days for evaluation of IL-1β. The results were analyzed and compared by using repeated measures ANOVA, paired t test, and independent two-sample t test (α=0.05). Result: The results showed that chewing gum significantly affected the SBI and API ( p & 0.001). Paired t test showed that the two groups were significantly different regarding the mean changes of SBI and API at different periods of 1-7, 1-21, and 7-21 ( p & 0.001). Concerning IL-1β, the repeated measures ANOVA revealed that the effect of chewing gum was significant ( p &0.001). Moreover, paired t-test represented no significant difference between the mean changes of IL-1β within 1-21 day ( p = 0.086). Conclusion: The green tea chewing gum improved the SBI and API and effectively reduced the level of IL-1β. Keywords ● Green Tea? ● Gingivitis? ● Plaque Index
机译:问题陈述:根据以前的研究,绿茶提取物的成分可以抑制多种革兰氏阳性和阴性细菌的生长,可能有助于控制口腔感染。目的:本研究的目的是确定绿茶口香糖对牙龈炎患者的牙菌斑和牙龈发炎率的影响。资料和方法:在该双盲随机对照临床试验中,选择了45例广义边缘性牙龈炎患者,将其分为两组:绿茶(23)和安慰剂(22)口香糖。患者每天咀嚼两个口香糖,持续15分钟,持续三个星期。在基线,第7天和第21天后研究沟出血指数(SBI)和近似菌斑指数(API)。在21天之前和之后进行唾液采样以评估IL-1β。使用重复测量方差分析,配对t检验和独立的两次样本t检验(α= 0.05)对结果进行分析和比较。结果:结果表明口香糖显着影响SBI和API(p <0.001)。配对t检验表明,两组在1-7、1-21和7-21的不同时期,SBI和API的平均变化显着不同(p <0.001)。关于IL-1β,重复测量ANOVA显示口香糖的作用是显着的(p <0.001)。此外,配对t检验在1-21天内IL-1β的平均变化之间无显着差异(p = 0.086)。结论:绿茶口香糖可改善SBI和API,并有效降低IL-1β水平。关键字●绿茶? ●牙龈炎? ●菌斑指数

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