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首页> 外文期刊>Journal of dermatology and cosmetic. >Determination of properties and evaluation of sun protective effects of saffron and safranal nanoliposomes
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Determination of properties and evaluation of sun protective effects of saffron and safranal nanoliposomes

机译：藏红花和藏红花纳米脂质体的性质测定和防晒作用评估

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Background and aim: Saffron possesses a lot of medical applications in traditional medicine. One of its properties is ultraviolet (UV) light absorption. The aim of this study was preparation, determination of properties and investigating sun protevtive effects of nanoliposomes containing saffron extract and safranal, a substance existing in saffron.Methods: Nanoliposomal hydroalcoholic extract of saffron stigma in concentrations 2%, 4%, 8% and nanoliposomal safranal in concentrations 0.25% , 0.5% and 1% were prepared. Standard lotion of homosalate 8% was used according to FDA standards for sun protection factor (SPF) determination and assessment of accuracy of the method. SPFs of substances were calculated in vitro by diluted solvent method using Mansur, et al equation and absorptiometry.Results: SPf of Nanoliposomal saffron 8% extract was significantly higher than standard sunscreen homosalate with similar concentration. SPFs of safranal (1% and 0.5%) component of saffron were significantly higher than the standard sunscreen homosalate 8%.Conclusion: Saffron can act as a sunscreen. Safranal existing in saffron is much more sun protective than standard substance, homosalate 8%. Thus , the safranal existing in saffron may have significant sun protective effect in low concentration if encapsulated in liposome.
机译：背景与目的：藏红花在传统医学中具有许多医学应用。其特性之一是紫外线（UV）吸收。这项研究的目的是制备，确定性质和研究含有藏红花提取物和藏红花的物质-藏红花的纳米脂质体的防晒作用。方法：藏红花柱头的纳米脂质体水醇提取物，浓度分别为2％，4％，8％和纳米脂质体制备浓度为0.25％，0.5％和1％的子。根据FDA标准，使用8％的标准乳清液进行防晒系数（SPF）的测定和方法准确性的评估。结果：纳米脂质体藏红花8％提取物的SPf值明显高于标准浓度的标准防晒霜的水乳清液，采用Mansur等人的方程和吸光光度法通过稀释溶剂法体外计算了物质的SPF。藏红花的fra（分别为1％和0.5％）成分的SPF显着高于标准防晒霜的8％（均值）。结论：藏红花可作为防晒霜。藏红花中存在的藏红花比标准物质（纯合8％）具有更好的防晒保护。因此，藏在藏红花中的藏红花如果包裹在脂质体中，可能在低浓度下具有明显的防晒作用。

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