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首页> 外文期刊>Journal of Dentistry >Evaluation of Vessels Density and the Clinicopathological Features of Oral Pyogenic Granuloma and its Histopathologic Subtypes
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Evaluation of Vessels Density and the Clinicopathological Features of Oral Pyogenic Granuloma and its Histopathologic Subtypes

机译：口腔化脓性肉芽肿及其组织病理亚型的血管密度和临床病理特征评估

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Statement of Problem: Due to the clinicopathologic similarity of pyogenic granuloma to some neoplastic or hamartomatouse lesion, vascular density can represent some biological behaviors of this lesion. Purpose: This study aimed to evaluate the density of the vessels and the clinicopathological features of oral pyogenic granuloma (PG) and its histopathologic subtypes. Materials &Methods: Information about age, sex, site, size, duration and the presence of surface ulceration in total and in two histopathologic subtypes (lobular and non-lobular) were collected From 94 PG files in the archives and were compared. Vessel counting was performed on H&E slides and the density of the vessels was compared in two subtypes, two genders and ulcerated and non-ulcerated groups using Independent Samples T- test. Results: Pyogenic granuloma comprised 4.5 percent of all the lesions. The male to female ratio was 1:1.7. The mean age of the patients was 27.99 years and the most frequent involved site was the gingiva (84%). The Non-LCH lesions were more than LCH. Post- mandibular gingiva in the LCH group and the anterior portion of the maxillary gingiva were the most locations of involvement. The mean duration of the presence of the lesion in Non-LCH was more than that in LCH. Surface ulceration in Non-LCH (89.4%) was more than LCH (78.6%). Although the mean density of the vessels was equal in both males and females; there was a significant difference in the lesions with or without surface ulcerations ( p =0.01). However there was no significant difference between the lobular and non-lobular groups. Conclusion: The site of the lesion, duration, and the lower cases with surface ulceration in the LCH form can be in contrast with reactive nature of this subtype, showing similarity to tumoral or developmental lesions. Gender does not influence the density of blood vessels in PG but surface ulceration can influence it. Key words: Pyogenic granuloma, Lobular and non-lobular capillary hemangioma
机译：问题陈述：由于化脓性肉芽肿与某些肿瘤性或错构瘤性病变的临床病理相似性，血管密度可以代表该病变的某些生物学行为。目的：本研究旨在评估口腔化脓性肉芽肿（PG）及其组织病理亚型的血管密度和临床病理特征。材料和方法：从档案中的94个PG文件中收集有关年龄，性别，部位，大小，持续时间以及表面溃疡的总数以及两种组织病理学亚型（小叶和非小叶）的信息，并进行比较。在H＆amp; E载玻片上进行血管计数，并使用Independent Samples T-检验比较两个亚型，两个性别以及溃疡和非溃疡组的血管密度。结果：化脓性肉芽肿占所有病变的4.5％。男女比例为1：1.7。患者的平均年龄为27.99岁，最常受累的部位是牙龈（84％）。非LCH病变多于LCH。 LCH组的下颌后牙龈和上颌牙龈的前部受累最多。 Non-LCH中病变存在的平均持续时间大于LCH中。非LCH（89.4％）的表面溃疡大于LCH（78.6％）。尽管雄性和雌性的血管平均密度是相等的;有或没有表面溃疡的病灶差异显着（p = 0.01）。但是，小叶和非小叶组之间没有显着差异。结论：LCH形式的病变部位，持续时间和表面溃疡程度较低的病例可与该亚型的反应性形成对比，表现出与肿瘤或发育性病变相似。性别不会影响PG中血管的密度，但表面溃疡会影响它。关键词：化脓性肉芽肿，小叶和非小叶性毛细血管瘤

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