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首页> 外文期刊>Journal of Dermatological Case Reports >Successful treatment of bullous lichen planus with acitretin monotherapy. Review of treatment options for bullous lichen planus and case report.
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Successful treatment of bullous lichen planus with acitretin monotherapy. Review of treatment options for bullous lichen planus and case report.

机译：阿维A单药成功治疗大疱性扁平苔藓。审查大疱性扁平苔藓的治疗选择和病例报告。

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BackgroundBullous lichen planus (BLP) is a rare variant of lichen planus, characterized by the development of vesicular and bullous lesions, of skin, nails, hair and/or mucosa.Main observationsWe present a case of 63-year-old woman with BLP, unresponsive to previous therapies with topical corticosteroids, topical calcipotriol, antihistamines and oral cyclosporine (4 mg/kg/day for 4 months). She was already receiving treatment for arterial hypertension, hyperlipidemia, atrial fibrillation and uncontrolled diabetes mellitus. Acitretin was administered for 5 months with complete remission of BLP lesions and no major side effects.ConclusionsThis is probably the first reported case of BLP treated with acitretin monotherapy. In this case acitretin was an efficacious and well-tolerated therapeutic option for BLP.
机译：背景牛扁平苔藓（BLP）是一种罕见的扁平苔藓变体，其特征是皮肤，指甲，头发和/或粘膜的水疱和大疱性病变发展。主要观察结果我们发现一例63岁的BLP女性患者，对以前使用局部皮质类固醇，局部卡泊三醇，抗组胺药和口服环孢霉素的治疗无反应（4毫克/千克/天，持续4个月）。她已经接受了动脉高血压，高脂血症，心房纤颤和不受控制的糖尿病的治疗。 Acitretin给药5个月，BLP病变完全缓解，无重大副作用。结论这可能是第一个报道的Acitretin单药治疗BLP病例。在这种情况下，acitretin是BLP的一种有效且耐受良好的治疗选择。

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