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首页> 外文期刊>Journal of Environmental Chemistry and Ecotoxicology >Toxic stress and hematological effects of nickel on African catfish, Clarias gariepinus, fingerlings
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Toxic stress and hematological effects of nickel on African catfish, Clarias gariepinus, fingerlings

机译：镍对非洲cat鱼，非洲aria鱼，鱼种的毒性和血液学影响

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摘要

This laboratory study assessed the effects of nickel on the behaviour and some blood parameters of African catfish,Clarias gariepinus,after a 96 h semi static method with a view to determining the safe concentration effect of the metal physiological functions of the fish.The mortality rate increased with increased concentrations of toxicants. The 96 h median lethal concentration (96 h LC50) was 8.87mg Ni/l using the logarithmic method with dose-mortality regression line Y (% mortality) = 174.74 (log Concentration) – 97.711. All the blood parameters (erythrocyte, leucocytes, hematocrit and hemoglobin count) decreased with increasing concentration of toxicant and become significantly lower (P 0.05) at higher concentration when compared with the control. The derived hematological indices of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were equally lowered. It is believed that observed depression in hematocrit and hemoglobin values coupled with decreased and deformed erythrocytes are obvious signs of anaemia. In conclusion, the changes observed indicate that hematological parameters can be used as an indicator of Ni related stress in fish on exposure to elevated Ni levels.
机译：这项实验室研究通过96小时半静态方法评估了镍对非洲cat鱼行为和某些血液参数的影响，以确定鱼的金属生理功能的安全浓度效应。死亡率随着毒物浓度的增加而增加。使用对数方法，剂量-死亡率回归线Y（％死亡率）= 174.74（对数浓度）– 97.711，使用对数方法的96小时中位致死浓度（96小时LC50）为8.87mg Ni / l。与对照相比，所有血液参数（红细胞，白细胞，血细胞比容和血红蛋白计数）均随着毒物浓度的增加而降低，并在较高浓度时显着降低（P <0.05）。平均血红细胞体积（MCV），平均血红蛋白（MCH）和平均血红蛋白浓度（MCHC）的血液学指标均降低。据信，观察到的血细胞比容和血红蛋白值降低，以及红细胞减少和变形是贫血的明显迹象。总之，观察到的变化表明，血液学参数可以用作指示鱼类在暴露于高水平的镍水平下与镍相关的应激的指标。

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