Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment

Goukasian N.; Porat S.; Blanken A.; Avila D.; Zlatev D.; Hurtz S.; Hwang K.S.; Pierce J.; Joshi S.H.; Woo E.; Apostolova L.G.

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Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment

机译：有或没有轻度认知障碍的成年人海马萎缩和心室扩大的认知相关性

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We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy and ventricular enlargement using the radial distance method.Bilateral hippocampal atrophy was associated with baseline and longitudinal memory performance. Left hippocampal atrophy predicted longitudinal decline in visuospatial function. The multidomain ventricular analysis did not reveal any significant predictors.

机译：我们分析了来自58名认知正常和101名轻度认知障碍受试者的结构磁共振成像数据。我们采用一般线性回归模型通过径向距离法研究认知功能与海马萎缩与脑室扩大之间的关系。双侧海马萎缩与基线和纵向记忆表现有关。左海马萎缩预测视觉空间功能的纵向下降。多域心室分析没有发现任何重要的预测因素。

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《Dementia and Geriatric Cognitive Disorders Extra》 |2019年第2期|共13页
作者
Goukasian N.; Porat S.; Blanken A.; Avila D.; Zlatev D.; Hurtz S.; Hwang K.S.; Pierce J.; Joshi S.H.; Woo E.; Apostolova L.G.;
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中图分类临床医学;
关键词
Alzheimer’s diseaseMild cognitive impairmentImagingMRIHippocampal atrophyVentricular enlargement;

机译：阿尔茨海默氏病轻度认知障碍影像MRI海马萎缩心室扩大;

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1. Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer disease [J] . ApostolovaL.G., GreenA.E., BabakchanianS., Alzheimer disease and associated disorders . 2012,第1期

机译：正常衰老，轻度认知障碍（MCI）和阿尔茨海默氏病患者的海马萎缩和心室扩大
2. Hippocampal and cortical atrophy in amyloid-negative mild cognitive impairments: Comparison with amyloid-positive mild cognitive impairment [J] . YeB.S., SeoS.W., KimC.H., Neurobiology of Aging: Experimental and Clinical Research . 2014,第2期

机译：淀粉样蛋白阴性轻度认知障碍的海马和皮质萎缩：与淀粉样蛋白阳性轻度认知障碍的比较
3. Cognitive Correlates of Digital Clock Drawing Metrics in Older Adults with and without Mild Cognitive Impairment [J] . Dion Catherine, Arias Franchesca, Amini Shawna, Journal of Alzheimer's disease: JAD . 2020,第1期

机译：具有轻度认知障碍的老年人数字时钟绘制度量的认知相关性
4. Ability to Manage Everyday Technology: A Comparison of People with Dementia or Mild Cognitive Impairment and Older Adults without Cognitive Impairment [C] . Camilla MALINOWSKY, Ove ALMKVIST, Anders KOTTORP, Association for the Advancement of Assistive Technology in Europe . 2009

机译：管理日常技术的能力：对痴呆或轻度认知障碍和老年人的比较没有认知障碍的老年人
5. Using Multimodal Imaging to Examine Clinical and Cognitive Correlates of Mild Cognitive Impairment and Alzheimer's Disease [D] . Chung, Jun Ku. 2018

机译：使用多模态成像检查轻度认知障碍和阿尔茨海默氏病的临床和认知相关性
6. Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment [O] . Naira Goukasian, Shai Porat, Anna Blanken, 2019

机译：有或没有轻度认知障碍的成年人海马萎缩和心室扩大的认知相关性
7. Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment [O] . Michel J. Grothe, Helmut Heinsen, Edson Amaro, 2015

机译：基础前脑萎缩和相关皮质衰老中的认知相关性与轻度认知障碍

Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment

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