• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dementia and Geriatric Cognitive Disorders Extra >Frontotemporal Dementia in Southeast Asia: A Comparative Study
【24h】

Frontotemporal Dementia in Southeast Asia: A Comparative Study

机译：东南亚额颞叶痴呆：比较研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The clinical profile of frontotemporal dementia (FTD) in Southeast Asia is not known. We characterized and compared the demographic and clinical characteristics of FTD patients in Southeast Asia with North Asian and Western patients. Methods: The study included Southeast Asian FTD patients presenting to a tertiary neurology institute. Behavioral variant (bv-FTD) and language variant (lv-FTD) subtypes of FTD were diagnosed based on the Lund-Manchester criteria. The patients were characterized according to demographics, clinical, neuroimaging and longitudinal profiles. Results: Twenty-five bv-FTD and 19 lv-FTD patients were identified, with a female predominance ratio of 2:1 and a mean age of 56 years. The mean MMSE score was 16.2, and 88.4% of patients had memory symptoms. Over 5.1 ± 2.4 years of follow-up, 60% of bv-FTD and 36.8% of lv-FTD patients developed a second FTD syndrome. bv-FTD was the predominant type of FTD among Southeast Asians. Conclusion: FTD represents an important cause of young-onset dementia in Southeast Asia. Greater awareness of FTD is required to ensure early diagnosis and management.
机译：背景：东南亚额颞叶痴呆（FTD）的临床概况尚不清楚。我们对东南亚FTD患者与北亚和西方患者的人口统计学特征和临床特征进行了比较。方法：该研究包括就诊于三级神经病学研究所的东南亚FTD患者。根据Lund-Manchester标准诊断FTD的行为变异（bv-FTD）和语言变异（lv-FTD）亚型。根据人口统计学，临床，神经影像学和纵向特征对患者进行了表征。结果：确定了25例bv-FTD患者和19例lv-FTD患者，女性优势比为2：1，平均年龄为56岁。 MMSE平均得分为16.2，并且88.4％的患者有记忆症状。在5.1±2.4年的随访中，60％的bv-FTD患者和36.8％的lv-FTD患者出现了第二个FTD综合征。 bv-FTD是东南亚人中FTD的主要类型。结论：FTD是东南亚年轻型痴呆的重要原因。需要提高对FTD的认识，以确保及早诊断和管理。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号