Comparing Clinical Profiles in Alzheimer's Disease and Parkinson's Disease Dementia

Aarsland D.; Farlow M.R.; Grossberg G.T.; Meng X.; Schmitt F.; Somogyi M.

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Comparing Clinical Profiles in Alzheimer's Disease and Parkinson's Disease Dementia

机译：阿尔茨海默氏病和帕金森氏病痴呆的临床特征比较

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Background: Greater understanding of differences in baseline impairment and disease progression in patients with Alzheimer's disease (AD) and Parkinson's disease dementia (PDD) may improve the interpretation of drug effects and the design of future studies. Methods: This was a retrospective analysis of three randomized, double-blind rivastigmine databases (one in PDD, two in AD). Impairment on the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog), Alzheimer's Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale, 10-item Neuropsychiatric Inventory (NPI-10) and the ADCS-Clinical Global Impression of Change (CGIC) was compared [standardized difference (Cohen's d), similar if

机译：背景：对阿尔茨海默氏病（AD）和帕金森氏病痴呆症（PDD）患者的基线损伤和疾病进展差异的更多了解可能会改善药物作用的解释和未来研究的设计。方法：这是对三个随机，双盲rivastigmine数据库（PDD中一个，AD中两个）的回顾性分析。阿尔茨海默氏病评估量表认知亚量表（ADAS-cog）受损，阿尔茨海默氏病合作研究-日常生活活动量（ADCS-ADL）量表，10项神经精神病学量表（NPI-10）和ADCS临床全球印象比较了变化（CGIC）[标准差（Cohen d），如果

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《Dementia and Geriatric Cognitive Disorders Extra》 |2013年第1期|共10页
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Aarsland D.; Farlow M.R.; Grossberg G.T.; Meng X.; Schmitt F.; Somogyi M.;
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中图分类临床医学;
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5. Comparing Alzheimer's disease and vascular dementia profiles on neuropsychological tests among Japanese elders. [D] . Sakamoto, Maiko. 2009

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6. Comparing Clinical Profiles in Alzheimers Disease and Parkinsons Disease Dementia [O] . Martin R. Farlow, Frederick Schmitt, Dag Aarsland, 2013

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7. A role for the brain RAS in Alzheimer's and Parkinson's diseases [O] . John William Wright, Leen H Kawas, Joseph W Harding 2013

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8. Recognition and Initial Assessment of Alzheimer's Disease and Related Dementias.Clinical Practice Guideline Number 19; Early Identification of Alzheimer's Disease and Related Dementias. Quick Reference Guide for Clinicians Number 19; Early Alzheimer's Dis [R] . Costa, P. T., Williams, T. F., Albert, M. S., 1996

机译：阿尔茨海默病和相关痴呆的认可和初步评估。临床实践指南第19号;阿尔茨海默病及相关痴呆的早期鉴定。临床医生快速参考指南第19号;早期阿尔茨海默氏症

Comparing Clinical Profiles in Alzheimer's Disease and Parkinson's Disease Dementia

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