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首页> 外文期刊>Journal of Education and Health Promotion >Factors related to 6-month mortality after the first-ever stroke
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Factors related to 6-month mortality after the first-ever stroke

机译：首次中风后6个月死亡率的相关因素

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BACKGROUND AND OBJECTIVE: Stroke is the second leading cause of death worldwide and the number of stroke cases has increased remarkably over the last 20 years. This study aimed at identifying predictors of with 6-month mortality of first-ever stroke patients and the factors contributing to it in East Azerbaijan province. MATERIALS AND METHODS: A closed cohort study was carried out from April 2014 to December 2014. All cases of first-ever diagnosed stroke were included in the study. Any transient ischemic attack, silent brain infarctions, and the stroke cases which were neither associated with trauma, blood disease nor with malignancy were excluded from the study. The variables of this study include participants' demographic characteristics, stroke severity National Institutes of Health Stroke Scale (NIHSS), and stroke risk factors. Patients were followed up within 6 months. To determine the survival time, the log-rank method was applied to compare intergroup differences. The tests include the univariate and multivariate analysis Cox regression. P 0.05 were considered as statistically significant. RESULTS: A total of 576 cases of stroke were included in this study. Average age of ischemic and hemorrhagic stroke was 70.15 ± 13.0 and 67.79 ± 12.69, respectively. Case-fatality rate (CFR) of stroke patients was 49.2 and 21.7% in hemorrhagic and ischemic stroke types, respectively. Factors contributing to stroke mortality events include the severity of stroke (NIHSS categories 15–19 and ≥20), age over 65, being female, high body mass index and hyperlipidemia. In the final model, the severity of stroke (with NIHSS 15–19 with hazard ratio (HR) 4.22 (95% confidence interval [CI] 2.36–7.56) and NIHSS ≥20 with HR 5.34 (95% CI: 2.81–10.12) and age above 65 with HR 1.61 (95% CI: 1.02–2.51) were the most important predictors of 6-month mortality. CONCLUSION: Severity of stroke by NIHSS was the most prominent factor in stroke patients' mortality. By increasing the follow-up time, a better evaluation of the predictors of mortality after stroke can be achieved.
机译：背景与目的：中风是全球第二大死亡原因，在过去的20年中，中风病例的数量显着增加。这项研究的目的是确定东阿塞拜疆省首例中风患者6个月死亡率的预测因素及其成因。材料与方法：2014年4月至2014年12月进行了一项封闭队列研究。该研究包括所有首次诊断为中风的病例。该研究不包括任何短暂性缺血发作，无脑梗塞以及与创伤，血液病或恶性肿瘤无关的中风病例。这项研究的变量包括参与者的人口统计学特征，中风严重性，美国国立卫生研究院中风量表（NIHSS）和中风危险因素。对患者进行了6个月的随访。为了确定存活时间，采用对数秩方法比较组间差异。测试包括单变量和多变量分析Cox回归。 P <0.05被认为具有统计学意义。结果：本研究共包括576例中风病例。缺血性和出血性中风的平均年龄分别为70.15±13.0和67.79±12.69。在出血性和缺血性中风类型中风患者的病死率（CFR）分别为49.2和21.7％。导致中风死亡事件的因素包括中风的严重程度（NIHSS类别15-19和≥20），65岁以上的女性，高体重指数和高脂血症。在最终模型中，中风的严重程度（使用NIHSS 15-19，危险比（HR）4.22（95％置信区间[CI] 2.36-7.56）和NIHSS≥20，HR 5.34（95％CI：2.81-10.12） 65岁及以上，HR 1.61（95％CI：1.02-2.51）是6个月死亡率的最重要预测指标。结论：NIHSS的卒中严重程度是卒中患者死亡率的最主要因素。随着时间的流逝，可以更好地评估中风后死亡率的预测指标。

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