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Periaortic lymphoma in a cat

机译:猫的早老性淋巴瘤

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A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia. Clinicopathological investigations revealed non-regenerative anaemia (haematocrit 0.17 l/l; reference interval [RI] 0.24a??0.45 l/l) and increased feline pancreatic lipase concentration (Spec fPL test [IDEXX] 8.3 ??g/l; RI 0.1a??3.5 ??g/l). Feline leukaemia virus antigen and feline immunodeficiency virus antibody tests were negative. Thoracic and abdominal imaging revealed a soft tissue structure in the area of the thoracoabdominal aorta. CT confirmed a periaortic contrast-enhancing mass extending from the level of T9a??L2, with associated intervertebral infiltration at the level of T11a??T12. Post-mortem examination confirmed the presence of a solid, white, multinodular, well-demarcated mass encircling the aorta extending from T9a??L2. Based on histopathology and immunohistochemistry, a diagnosis of B-cell lymphoma was made. Lymphoma was also identified histopathologically within the kidneys and spleen. Evidence of mild Wallerian degeneration was present within the spinal cord, indicating compression at the level of the periaortic mass.
机译:出现了一只14岁的绝育雄性暹罗猫,有3个月的嗜睡,食欲不振,脱水,后肢共济失调和后肢间歇性本体感受缺陷的病史。体格检查发现身体状况评分低(1.75 / 5),苍白和双侧基底II / VI级收缩期心脏杂音。神经学检查发现后肢共济失调,后肢肌肉严重萎缩,后肢间歇性本体感受性缺陷和正反运动。临床病理学检查显示非再生性贫血(红细胞压积0.17 l / l;参考区间[RI] 0.24a ?? 0.45 l / l)和猫胰腺脂肪酶浓度升高(Spec fPL测试[IDEXX] 8.3 ?? g / l; RI 0.1) a≤3.5≤g/ l)。猫白血病病毒抗原和猫免疫缺陷病毒抗体测试均为阴性。胸部和腹部影像学显示胸腹主动脉区域有软组织结构。 CT证实了从T9a→L2水平延伸的腹主动脉造影增强肿块,并在T11a→T12水平伴有椎间浸润。验尸证实,存在一个坚实的,白色的,多结节的,划定的肿块,环绕着从T9a ?? L2延伸的主动脉。基于组织病理学和免疫组织化学,诊断为B细胞淋巴瘤。在肾脏和脾脏中也从组织病理学上鉴定出淋巴瘤。脊髓内存在轻度沃勒变性的证据,表明在腹主动脉包块水平受压。

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