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QTL mapping for combining ability in different population-based NCII designs: a simulation study

机译:结合不同人群基于NCII设计的能力的QTL映射:模拟研究

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The NCII design (North Carolina mating design II) has been widely applied in studies of combining ability and heterosis. The objective of our research was to estimate how different base populations, sample sizes, testcross numbers and heritability influence QTL analyses of combining ability and heterosis. A series of Monte Carlo simulation experiments with QTL mapping were then conducted for the base population performance, testcross population phenotypic values and the general combining ability (GCA), specific combining ability (SCA) and Hmp (midparental heterosis) datasets. The results indicated that:increasing the number of testers did not necessarily enhance the QTL detection power for GCA, but it was significantly related to the QTL effect.
机译:NCII设计(北卡罗莱纳州交配设计II)已广泛用于结合能力和杂种优势的研究。我们研究的目的是估计不同的基本种群,样本量,testcross数量和遗传力如何影响结合能力和杂种优势的QTL分析。然后进行了一系列带有QTL映射的蒙特卡罗模拟实验,用于基本种群性能,testcross种群表型值和一般结合能力(GCA),比结合能力(SCA)和Hmp(中父母杂种优势)数据集。结果表明:增加测试人员数量并不一定能增强GCA的QTL检测能力,但与QTL效果显着相关。

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