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首页> 外文期刊>Journal of Ginseng Research >Ginsenosides: the need to move forward from bench to clinical trials
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Ginsenosides: the need to move forward from bench to clinical trials

机译：人参皂甙：需要从临床试验过渡到临床试验

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摘要

Panax ginseng , known as Koran ginseng, one of the most commonly used traditional plants, has been demonstrated to show a wide range of pharmacological applications. Ginsenosides are the major active ingredients found in ginseng and are responsible for the biological and pharmacological activities, such as antioxidation, antiinflammation, vasorelaxation, and anticancer actions. Existing studies have mostly focused on identifying and purifying single ginsenosides and investigating pharmacological activities and molecular mechanisms in cells and animal models. However, ginsenoside studies based on clinical trials have been very limited. Therefore, this review aimed to discuss the currently available clinical trials on ginsenosides and provide insights and future directions for developing ginsenosides as efficacious and safe drugs for human disease.
机译：人参，被称为古兰经人参，是最常用的传统植物之一，已被证明具有广泛的药理应用。人参皂苷是人参中的主要活性成分，并负责生物和药理活性，例如抗氧化，抗炎，血管舒张和抗癌作用。现有研究主要集中于鉴定和纯化单一人参皂苷，以及研究细胞和动物模型中的药理活性和分子机制。但是，基于临床试验的人参皂甙研究非常有限。因此，本综述旨在讨论人参皂苷的当前可用临床试验，并为开发人参皂苷作为对人类疾病的有效和安全的药物提供见识和未来的方向。

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