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首页> 外文期刊>Journal of Global Health >Endoscopic Submucosal Tunnel Dissection for Upper Gastrointestinal Submucosal Tumors Originating from the Muscularis Propria Layer: A Single-Center Study
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Endoscopic Submucosal Tunnel Dissection for Upper Gastrointestinal Submucosal Tumors Originating from the Muscularis Propria Layer: A Single-Center Study

机译：内镜下黏膜下隧道剥离术治疗源自固有肌层的上消化道黏膜下肿瘤：单中心研究

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Background/AimsIn recent years, endoscopic submucosal tunnel dissection (ESTD) has gained popularity worldwide. The aim of this study was to evaluate the safety and efficacy of ESTD in treating upper gastrointestinal submucosal tumors (SMTs) in a large-volume endoscopic center.MethodsPatients with SMTs were enrolled in this study between January 2012 and January 2015. Demographic data, clinical data, and treatment outcome were collected and analyzed.ResultsSeventy SMTs originating from the muscularis propria (MP) layer were identified in 69 patients. All patients successfully underwent the ESTD procedure. The mean procedure time was 49.0±29.5 minutes, and the mean tumor size was 18.7±7.2 mm. Among all lesions, the majority (70.0%) were located in the esophagus, 12.9% in the cardia, and 17.1% in the stomach. Complete resection was achieved in 67 lesions (95.7%). Perforation occurred in three patients (4.3%), who were treated by endoclips. Pneumothorax occurred in two patients (2.9%) and was successfully managed by thoracic drainage. During a median follow-up of 18.1 months, patients were free of local recurrence or distant metastasis.ConclusionsOur results demonstrated the feasibility and safety of ESTD in treating upper gastrointestinal SMTs originating from the MP layer. Large-scale comparative studies with other treatment methods should be conducted in the future.Keywords: Endoscopic submucosal tunnel dissection, Submucosal tumor, Upper gastrointestinal, Treatment outcome
机译：背景/目的近年来，内镜下黏膜下隧道剥离术（ESTD）在世界范围内得到普及。这项研究的目的是评估ESTD在大容量内窥镜中心治疗上消化道粘膜下肿瘤（SMT）的安全性和有效性。方法研究对象是2012年1月至2015年1月期间患有SMT的患者。人口统计学，临床结果69例患者中发现了70例源自固有肌层（MP）的SMT。所有患者均成功接受了ESTD程序。平均手术时间为49.0±29.5分钟，平均肿瘤大小为18.7±7.2mm。在所有病变中，大多数（70.0％）位于食道，,门为12.9％，胃为17.1％。 67个病灶（95.7％）完全切除。经内窥镜治疗的三名患者（4.3％）发生穿孔。气胸发生在两名患者（2.9％）中，并通过胸腔引流成功治疗。在中位随访期18.1个月中，患者无局部复发或远处转移。结论我们的结果证明了ESTD治疗源自MP层的上消化道SMT的可行性和安全性。关键词：内镜下黏膜下隧道剥离术，黏膜下肿瘤，上消化道，治疗效果

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