...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Hainan Medical University >Effect of combined sevoflurane-propofol-fentanyl anesthesia on the postoperative emergence agitation and neuroendocrine compensation in children with tonsillectomy
【24h】

Effect of combined sevoflurane-propofol-fentanyl anesthesia on the postoperative emergence agitation and neuroendocrine compensation in children with tonsillectomy

机译：七氟醚-异丙酚-芬太尼联合麻醉对扁桃体切除术患儿术后躁动及神经内分泌补偿的影响

获取原文
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: To study the effect of combined sevoflurane-propofol-fentanyl anesthesia onthe postoperative emergence agitation and neuroendocrine compensation in children withtonsillectomy. Methods: 78 patients who accepted tonsillectomy in our hospital between May2013 and January 2016 were selected and randomly divided into two groups, the observationgroup received sevoflurane-propofol-fentanyl anesthesia, and the control group receivedketamine-propofol-fentanyl anesthesia, 39 in each group. Before anesthesia, before extubationand at recovery period after extubation, serum was collected respectively to determine thelevels of inflammatory factors, stress hormones and renin-angiotensin-aldosterone system(RAAS) system hormones. Results: Before anesthesia and before extubation, the differencesin serum C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β),IL-6, IL-10, cortisol (Cor), norepinephrine (NE), epinephrine (E), free triiodothyronine (FT3),free thyroxine (FT4), renin (PRA), angiotensin II (AT-II) and aldosterone (ALD) levels werenot statistically significant between two groups of patients (P0.05); at recovery period, serumCRP, TNF-α, IL-1β, IL-6, IL-10, Cor, NE, E, FT3, FT4, PRA, AT-II and ALD levels of bothgroups were significantly higher than those before anesthesia and before extubation (P0.05),and serum CRP, TNF-α, IL-1β, IL-6, IL-10, Cor, NE, E, FT3, FT4, PRA, AT-II and ALDlevels of observation group at recovery period were significantly lower than those of controlgroup (P0.05). Conclusion: Combined sevoflurane-propofol-fentanyl anesthesia for childrenwith tonsillectomy can alleviate the inflammatory response and stress response caused byemergence agitation.
机译：目的：研究七氟醚-异丙酚-芬太尼联合麻醉对小儿扁桃体切除术后术后躁动及神经内分泌补偿的影响。方法：选择2013年5月至2016年1月在我院接受扁桃体切除术的78例患者，随机分为两组，观察组给予七氟醚-异丙酚-芬太尼麻醉，对照组接受氯胺酮-异丙酚-芬太尼麻醉，每组39例。麻醉前，拔管前和拔管后恢复期分别收集血清，测定炎症因子，应激激素和肾素-血管紧张素-醛固酮系统（RAAS）系统激素的水平。结果：麻醉前和拔管前，血清C反应蛋白（CRP），肿瘤坏死因子-α（TNF-α），白介素-1β（IL-1β），IL-6，IL-10，皮质醇（Cor）的差异），两组患者的去甲肾上腺素（NE），肾上腺素（E），游离三碘甲腺氨酸（FT3），游离甲状腺素（FT4），肾素（PRA），血管紧张素II（AT-II）和醛固酮（ALD）水平在统计学上均无统计学意义（P> 0.05）;在恢复期，两组的血清CRP，TNF-α，IL-1β，IL-6，IL-10，Cor，NE，E，FT3，FT4，PRA，AT-II和ALD水平均显着高于麻醉前和对照组。拔管前（P <0.05），观察组恢复时的血清CRP，TNF-α，IL-1β，IL-6，IL-10，Cor，NE，E，FT3，FT4，PRA，AT-II和ALD水平期间明显低于对照组（P <0.05）。结论：七氟醚-异丙酚-芬太尼联合麻醉可减轻儿童扁桃体切除术引起的炎症反应和应激反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号